Cat: PAX2000-12284

Recombinant Human TULP2 Protein,His

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Analytical Data

  • Gene name

    TULP2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TULP2; TUBL2; Tubby-related Protein 2; Cancer/testis antigen 65; CT65; Tubby-like Protein 2

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O00295

  • Expression Region

    1-520 aa

  • AA Sequence

    MSQDNDTLMR DILGHELAAM RLQKLEQQRR LFEKKQRQKR QELLMVQANP DASPWLWRSC LREERLLGDR GLGNPFLRKK VSEAHLPSGI HSALGTVSCG GDGRGERGLP TPRTEAVFRN LGLQSPFLSW LPDNSDAELE EVSVENGSVS PPPFKQSPRI RRKGWQAHQR PGTRAEGESD SQDMGDAHKS PNMGPNPGMD GDCVYENLAF QKEEDLEKKR EASESTGTNS SAAHNEELSK ALKGEGGTDS DHMRHEASLA IRSPCPGLEE DMEAYVLRPA LPGTMMQCYL TRDKHGVDKG LFPLYYLYLE TSDSLQRFLL AGRKRRRSKT SNYLISLDPT HLSRDGDNFV GKVRSNVFST KFTIFDNGVN PDREHLTRNT ARIRQELGAV CYEPNVLGYL GPRKMTVILP GTNSQNQRIN VQPLNEQESL LSRYQRGDKQ GLLLLHNKTP SWDKENGVYT LNFHGRVTRA SVKNFQIVDP KHQEHLVLQF GRVGPDTFTM DFCFPFSPLQ AFSICLSSFN

  • Molecular Weight

    58.6  kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

TULP2, or Tubby-Like Protein 2, is a member of the tubby protein family, which is characterized by its involvement in various cellular processes and its significant role in the nervous system. Research on TULP2 has gained prominence due to its association with several neurological disorders, particularly retinal degeneration and other neurodegenerative conditions. The understanding of TULP2 function has been accelerated by studies demonstrating its involvement in the regulation of lipid metabolism and vesicular trafficking, essential processes for neuronal health and function. Identifying the structural and functional properties of TULP2 is crucial for elucidating its precise role in these pathways. Recent advancements in recombinant protein techniques have enabled researchers to produce TULP2 in large quantities, allowing for detailed biochemical analyses and the development of potential therapeutic strategies. Through studies focusing on TULP2's interactions with other cellular components and its effects on cellular signaling, it is anticipated that a clearer picture will emerge regarding its contributions to cellular homeostasis and its implications in disease mechanisms. The ongoing research into TULP2 not only promises to enhance our understanding of tubby proteins but also aims to pave the way for innovative approaches in treating related neurodegenerative disorders.

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