Analytical Data
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基因名
TUBA3E
- Application
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别名
TUBA3E; Tubulin alpha-3E chain; Alpha-tubulin 3E) [Cleaved into: Detyrosinated tubulin alpha-3E chain]
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6PEY2
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表达区间
1-450 aa
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氨基酸序列
MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK HVPRAVFVDL EPTVVDEVRT GTYRQLFHPE QLITGKEDAA SNYARGHYTI GKEIVDLVLD RIRKLADLCT GLQGFLIFHS FGGGTGSGFA SLLMERLSVD YSKKSKLEFA IYPAPQVSTA VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL IGQIVSSITA SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN QMVKCDPRHG KYMACCMLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LVHKFDLMYA KWAFVHWYVG EGMEEGEFSE AREDLAALEK DCEEVGVDSV EAEAEEGEAY
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分子量
49.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TUBA3E, a member of the tubulin protein family, plays a crucial role in the polymerization and stabilization of microtubules, which are vital components of the cytoskeleton in eukaryotic cells. Research into TUBA3E has gained momentum due to its involvement in various cellular processes, including cell division, intracellular transport, and maintenance of cell shape. Abnormalities in tubulin proteins, including TUBA3E, have been linked to a range of diseases, such as cancer and neurodegenerative disorders. Recent studies have highlighted the importance of TUBA3E in neuronal development and its potential role as a biomarker for certain pathological conditions. Investigating the structure and function of recombinant TUBA3E proteins provides insights into their dynamic assembly and interaction with other microtubule-associated proteins. As researchers aim to develop targeted therapies for diseases associated with microtubule dysregulation, the recombination and characterization of TUBA3E hold promise for novel therapeutic strategies and a deeper understanding of cytoskeletal architecture and function.












