Cat: PAX2000-12239

Recombinant Human TTC26 Protein,His

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Analytical Data

  • Gene name

    TTC26

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TTC26; IFT56; Intraflagellar transport Protein 56; Tetratricopeptide repeat Protein 26; TPR repeat Protein 26

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    A0AVF1

  • Expression Region

    1-554 aa

  • AA Sequence

    MMLSRAKPAV GRGVQHTDKR KKKGRKIPKL EELLSKRDFT GAITLLEFKR HVGEEEEDTN LWIGYCAFHL GDYKRALEEY ENATKEENCN SEVWVNLACT YFFLGMYKQA EAAGFKASKS RLQNRLLFHL AHKFNDEKKL MSFHQNLQDV TEDQLSLASI HYMRSHYQEA IDIYKRILLD NREYLALNVY VALCYYKLDY YDVSQEVLAV YLQQIPDSTI ALNLKACNHF RLYNGRAAEA ELKSLMDNAS SSFEFAKELI RHNLVVFRGG EGALQVLPPL VDVIPEARLN LVIYYLRQDD VQEAYNLIKD LEPTTPQEYI LKGVVNAALG QEMGSRDHMK IAQQFFQLVG GSASECDTIP GRQCMASCFF LLKQFDDVLI YLNSFKSYFY NDDIFNFNYA QAKAATGNTS EGEEAFLLIQ SEKMKNDYIY LSWLARCYIM NKKPRLAWEL YLKMETSGES FSLLQLIAND CYKMGQFYYS AKAFDVLERL DPNPEYWEGK RGACVGIFQM IIAGREPKET LREVLHLLRS TGNTQVEYMI RIMKKWAKEN RVSI

  • Molecular Weight

    64.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

The TTC26 protein, part of the tetratricopeptide repeat (TPR) family, plays a pivotal role in various cellular processes, including protein folding, signaling, and regulation of enzymatic activity. Research into TTC26 has gained attention due to its potential implications in developmental biology and disease mechanisms, particularly in the context of genetic disorders and cancers. Investigations have revealed that TTC26 may influence cellular pathways linked to the maintenance of protein homeostasis and stress responses, suggesting its involvement in the regulation of key biological functions. Additionally, alterations in TTC26 expression or function have been implicated in pathological conditions, highlighting its importance as a potential biomarker or therapeutic target. Understanding the structure-function relationship of TTC26 through recombinant protein studies can provide insights into its biological roles and mechanisms, paving the way for innovative strategies in disease intervention. Overall, the exploration of TTC26 and its associated pathways is critical for elucidating the molecular underpinnings of various health conditions, as well as for developing targeted therapeutic approaches in the future.

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