Cat: PAX2000-12223

Recombinant Human TSPY2 Protein,His

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Analytical Data

  • Gene name

    TSPY2

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TSPY2; TSPYQ1Testis-specific Y-encoded Protein 2; Testis-specific Y-encoded Protein Q1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    A6NKD2

  • Expression Region

    1-308 aa

  • AA Sequence

    MRPEGSLTYR VPERLRQGSC GVGRAAQALV CASAKEGTAF RMEAVQEGAA GVESEQAALG EEAVLLLDDI MAEVEVVAEE EGLVERREEA QRAQQAVPGP GPMTPESALE ELLAVQVELE PVNAQARKAF SRQREKMERR RKPHLDRRGA VIQSVPGFWA NVIANHPQMS ALITDEDEDM LSYMVSLEVE EEKHRVHLCK IMLFFRSNPY FQNKVITKEY LVNITEYRAS HSTPIEWYPD YEVEAYRRRH HNSSLNFFNW FSDHNFAGSN KIAEILCKDL WRNPLQYYKR MKPPEEGTET SGDSQLLS

  • Molecular Weight

    35.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

TSPY2 (Testis-Specific Protein Y-Linked 2) is a gene located on the Y chromosome, playing a critical role in male germ cell development. Research has highlighted its involvement in spermatogenesis, and it has been implicated in various reproductive disorders and testicular cancer. The protein product of TSPY2 is believed to function as a transcription factor, influencing gene expression related to cell growth and differentiation. Due to its specific expression in the testis, TSPY2 serves as a potential biomarker for male fertility assessment and oncological studies concerning testicular tumors. Furthermore, its unique chromosomal localization has sparked interest in evolutionary biology, as it provides insights into Y chromosome evolution and sex determination processes. Understanding the structure and function of TSPY2 can enhance our knowledge of male reproductive health, paving the way for potential therapeutic strategies in addressing infertility and malignancies associated with the male reproductive system. Consequently, research on TSPY2 recombinant proteins aims to elucidate their biological roles and interactions, contributing to a deeper understanding of male reproductive physiology and its associated pathologies.

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