Analytical Data
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基因名
TSP50
- Application
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别名
Probable threonine protease PRSS50. EC:3.4.25.-. Cancer/testis antigen 20. Serine protease 50. Testis-specific protease-like Protein 50
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UI38
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表达区间
1-385 aa
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氨基酸序列
MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCVPKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQALALPAPSRTLLLALPLPLSLLAAL
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分子量
67.98 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TSP50, or Testis-Specific Protein 50, is a recently identified protein that plays a crucial role in spermatogenesis and male fertility. Research interest in TSP50 has increased due to its unique expression pattern, which is confined to the testis, making it a potential molecular marker for testicular function and a target for infertility treatments. The protein is thought to be involved in the regulation of gene expression essential for sperm development and maturation. Given the rising rates of male infertility globally, understanding the mechanisms underlying TSP50's functionality could pave the way for novel therapeutic approaches. Additionally, TSP50 may hold promise as a biomarker for certain testicular cancers, given its specific expression in germ cells. Studies focusing on the biochemical properties of TSP50, its interactions with other cellular proteins, and its regulatory pathways could provide insights into male reproductive health and identify potential targets for intervention in infertility and cancer therapies. Overall, TSP50 represents a significant focus of research aimed at unraveling its role in male reproductive biology and its potential applications in clinical settings.
