Analytical Data
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基因名
FAM83F
- Application
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别名
FAM83FProtein FAM83F
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NEG4
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表达区间
2-500aa
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氨基酸序列
AESQLNCLD EAHVNEKVTE AQAAFYYCER RRAALEALLG GGEQAYRERL KEEQLRDFLS SPERQALRAA WSPYEDAVPA ANARGKSKAK AKAPAPAPAE SGESLAYWPD RSDTEVPPLD LGWTDTGFYR GVSRVTLFTH PPKDEKAPHL KQVVRQMIQQ AQKVIAVVMD LFTDGDIFQD IVDAACKRRV PVYIILDEAG VKYFLEMCQD LQLTDFRIRN IRVRSVTGVG FYMPMGRIKG TLSSRFLMVD GDKVATGSYR FTWSSSHVDR NLLLLLTGQN VEPFDTEFRE LYAISEEVDL YRQLSLAGRV GLHYSSTVAR KLINPKYALV SGCRHPPGEM MRWAARQQRE AGGNPEGQEE GASGGESAWR LESFLKDLVT VEQVLPPVEP IPLGELSQKD GRMVSHMHRD LKPKSREAPS RNGMGEAARG EAAPARRFSS RLFSRRAKRP AAPNGMASSV STETSEVEFL TGKRPNENSS ADISGKTSPS SAKPSNCVIS
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分子量
55.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAM83F is a gene that encodes a member of the FAM83 family of proteins, which are implicated in various cellular processes including cell growth, differentiation, and tumorigenesis. Research on FAM83F has garnered attention due to its role in cancer biology, especially in breast cancer, where it has been identified as an oncogene that promotes tumor progression and metastasis. Elevated levels of FAM83F have been correlated with poor patient prognosis, making it a potential biomarker for cancer diagnosis and treatment response. The protein has been linked to the regulation of cellular signaling pathways, particularly those involved in the RAS-MAPK pathway, which is critical for cell proliferation and survival. Understanding the structure and function of the FAM83F protein can provide insights into its molecular mechanisms and interactions within the cell, offering new avenues for therapeutic targets. Additionally, the study of recombinant FAM83F proteins allows for the exploration of their functional roles in vitro and in vivo, facilitating the development of novel strategies for cancer intervention. Overall, FAM83F represents a promising focus for ongoing cancer research aimed at elucidating its contributions to tumorigenesis and exploring its potential as a target for therapeutic intervention.
