Analytical Data
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Gene name
FAM83F
- Application
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Alternative Names
FAM83FProtein FAM83F
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NEG4
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Expression Region
2-500aa
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AA Sequence
AESQLNCLD EAHVNEKVTE AQAAFYYCER RRAALEALLG GGEQAYRERL KEEQLRDFLS SPERQALRAA WSPYEDAVPA ANARGKSKAK AKAPAPAPAE SGESLAYWPD RSDTEVPPLD LGWTDTGFYR GVSRVTLFTH PPKDEKAPHL KQVVRQMIQQ AQKVIAVVMD LFTDGDIFQD IVDAACKRRV PVYIILDEAG VKYFLEMCQD LQLTDFRIRN IRVRSVTGVG FYMPMGRIKG TLSSRFLMVD GDKVATGSYR FTWSSSHVDR NLLLLLTGQN VEPFDTEFRE LYAISEEVDL YRQLSLAGRV GLHYSSTVAR KLINPKYALV SGCRHPPGEM MRWAARQQRE AGGNPEGQEE GASGGESAWR LESFLKDLVT VEQVLPPVEP IPLGELSQKD GRMVSHMHRD LKPKSREAPS RNGMGEAARG EAAPARRFSS RLFSRRAKRP AAPNGMASSV STETSEVEFL TGKRPNENSS ADISGKTSPS SAKPSNCVIS
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Molecular Weight
55.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FAM83F is a gene that encodes a member of the FAM83 family of proteins, which are implicated in various cellular processes including cell growth, differentiation, and tumorigenesis. Research on FAM83F has garnered attention due to its role in cancer biology, especially in breast cancer, where it has been identified as an oncogene that promotes tumor progression and metastasis. Elevated levels of FAM83F have been correlated with poor patient prognosis, making it a potential biomarker for cancer diagnosis and treatment response. The protein has been linked to the regulation of cellular signaling pathways, particularly those involved in the RAS-MAPK pathway, which is critical for cell proliferation and survival. Understanding the structure and function of the FAM83F protein can provide insights into its molecular mechanisms and interactions within the cell, offering new avenues for therapeutic targets. Additionally, the study of recombinant FAM83F proteins allows for the exploration of their functional roles in vitro and in vivo, facilitating the development of novel strategies for cancer intervention. Overall, FAM83F represents a promising focus for ongoing cancer research aimed at elucidating its contributions to tumorigenesis and exploring its potential as a target for therapeutic intervention.
