Analytical Data
-
基因名
MASP2
- Application
-
别名
MASP2；Mannan-binding lectin serine protease 2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O00187
-
表达区间
1-686aa
-
氨基酸序列
MRLLTLLGLLCGSVATPLGPKWPEPVFGRLASPGFPGEYANDQERRWTLT APPGYRLRLYFTHFDLELSHLCEYDFVKLSSGAKVLATLCGQESTDTERA PGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDIDECQVAPGEAP TCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPE YPRPYPKLSSCTYSISLEEGFSVILDFVESFDVETHPETLCPYDFLKIQT DREEHGPFCGKTLPHRIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPC PYPMAPPNGHVSPVQAKYILKDSFSIFCETGYELLQGHLPLKSFTAVCQK DGSWDRPMPACSIVDCGPPDDLPSGRVEYITGPGVTTYKAVIQYSCEETF YTMKVNDGKYVCEADGFWTSSKGEKSLPVCEPVCGLSARTTGGRIYGGQK AKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMG TLKRLSPHYTQAWSEAVFIHEGYTHDAGFDNDIALIKLNNKVVINSNITP ICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKCTA AYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVG GIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISDF
-
分子量
102 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human FAM82C Protein，His
Cat：PA2000-7560
Recombinant Human TSC2 Protein，GST
Cat：PAX2000-12207
Recombinant Human MAN1A1 Protein，His
Cat：PA1000-8444
Protein Description
MASP2 (MBL-associated serine protease 2) is a crucial component of the lectin pathway of the complement system, playing a significant role in innate immunity. This protease is involved in the activation of complement proteins, contributing to opsonization and clearance of pathogens. Research surrounding MASP2 has gained momentum due to its implications in various diseases, including autoimmune disorders, infections, and inflammatory conditions. Understanding MASP2's structure and function is vital for elucidating its role in immune responses and pathophysiology. Furthermore, studies on recombinant MASP2 proteins have provided insights into its enzymatic activity, substrate specificity, and interactions with other complement components. These investigations pave the way for potential therapeutic applications, as targeting MASP2 could offer new strategies for modulating immune responses in disease settings. As a result, the recombinant production and characterization of MASP2 are essential for both basic research and clinical applications, enhancing our understanding of its role in health and disease.
