Analytical Data
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基因名
TRIP4
- Application
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别名
Activating signal cointegrator 1; ASC 1; ASC-1; HsT17391; Thyroid hormone receptor interactor 4; Thyroid receptor interacting Protein 4; Thyroid receptor-interacting Protein 4; TR-interacting Protein 4; TRIP 4; TRIP-4; Trip4; TRIP4_HUMAN; ZC2HC5; Zinc finger C2HC5 type
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15650
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表达区间
2-581 aa
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氨基酸序列
AVAGAVSGE PLVHWCTQQL RKTFGLDVSE EIIQYVLSIE SAEEIREYVT DLLQGNEGKK GQFIEELITK WQKNDQELIS DPLQQCFKKD EILDGQKSGD HLKRGRKKGR NRQEVPAFTE PDTTAEVKTP FDLAKAQENS NSVKKKTKFV NLYTREGQDR LAVLLPGRHP CDCLGQKHKL INNCLICGRI VCEQEGSGPC LFCGTLVCTH EEQDILQRDS NKSQKLLKKL MSGVENSGKV DISTKDLLPH QELRIKSGLE KAIKHKDKLL EFDRTSIRRT QVIDDESDYF ASDSNQWLSK LERETLQKRE EELRELRHAS RLSKKVTIDF AGRKILEEEN SLAEYHSRLD ETIQAIANGT LNQPLTKLDR SSEEPLGVLV NPNMYQSPPQ WVDHTGAASQ KKAFRSSGFG LEFNSFQHQL RIQDQEFQEG FDGGWCLSVH QPWASLLVRG IKRVEGRSWY TPHRGRLWIA ATAKKPSPQE VSELQATYRL LRGKDVEFPN DYPSGCLLGC VDLIDCLSQK QFKEQFPDIS QESDSPFVFI CKNPQEMVVK FPIKGNPKIW KLDSKIHQGA KKGLMKQNKA V
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分子量
66.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Recombinant Human FAM65B Protein，GST
Cat：PA2000-7544
Recombinant Human TRIO Protein，GST
Cat：PAX2000-12186
Protein Description
TRIP4, or Thyroid hormone Receptor Interacting Protein 4, is a crucial protein involved in the regulation of various cellular processes, including gene expression and signal transduction pathways. Initially identified as a coactivator for thyroid hormone receptors, TRIP4 has garnered attention for its role in mediating the effects of thyroid hormones on metabolism, development, and differentiation. Recent studies suggest that TRIP4 is not only associated with thyroid hormone signaling but also interacts with other nuclear receptors, thus influencing diverse biological functions. Additionally, its involvement in various diseases, including cancer and metabolic disorders, highlights the importance of understanding TRIP4's mechanisms of action. Researchers have focused on elucidating the structure-function relationships of TRIP4 to better comprehend its regulatory roles and potential as a therapeutic target. The advancement in recombinant protein technology has enabled the production and characterization of TRIP4, facilitating in-depth studies of its structure, interactions, and impact on cellular pathways. Such insights could lead to novel strategies for treating diseases linked to dysregulated thyroid hormone signaling and TRIP4 dysfunction. Overall, the ongoing research on TRIP4 aims to unravel its intricate biological roles and contribute to our understanding of its significance in health and disease.
