Analytical Data
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基因名
FAM63A
- Application
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别名
Deubiquitinating enzyme MINDY-1; FA63A_HUMAN; FAM 63A; FAM63A; Family with sequence similarity 63 member A; FLJ11280; FLJ43504; Hypothetical protein LOC55793; KIAA1390; Protein FAM63A; RP11 316M1.5; Ubiquitin carboxyl-terminal hydrolase MINDY-1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N5J2
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表达区间
1-469aa
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氨基酸序列
MEYHQPEDPAPGKAGTAEAVIPENHEVLAGPDEHPQDTDARDADGEAREREPADQALLPSQCGDNLESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPEKQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
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分子量
78.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAM63A is a gene encoding a protein that is involved in various cellular processes, including cell proliferation, differentiation, and the response to stress. Recent studies have highlighted the importance of FAM63A in cancer biology, where its aberrant expression correlates with tumor progression and poor prognosis in several cancer types. The understanding of FAM63A's function has been furthered through the development of recombinant FAM63A protein, which enables researchers to study its biochemical properties and interactions with other cellular proteins. Purification of this recombinant protein allows for detailed analyses, such as examining its role in cell signaling pathways and its potential as a biomarker or therapeutic target. Additionally, investigations into the structural characteristics of FAM63A may reveal insights into its mechanism of action and how alterations in its function contribute to disease. Overall, the research on recombinant FAM63A protein is critical for elucidating its biological significance and potential implications in cancer therapy and diagnostics.
