Analytical Data
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Gene name
FAM63A
- Application
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Alternative Names
Deubiquitinating enzyme MINDY-1; FA63A_HUMAN; FAM 63A; FAM63A; Family with sequence similarity 63 member A; FLJ11280; FLJ43504; Hypothetical protein LOC55793; KIAA1390; Protein FAM63A; RP11 316M1.5; Ubiquitin carboxyl-terminal hydrolase MINDY-1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N5J2
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Expression Region
1-469aa
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AA Sequence
MEYHQPEDPAPGKAGTAEAVIPENHEVLAGPDEHPQDTDARDADGEAREREPADQALLPSQCGDNLESPLPEASSAPPGPTLGTLPEVETIRACSMPQELPQSPRTRQPEPDFYCVKWIPWKGEQTPIITQSTNGPCPLLAIMNILFLQWKVKLPPQKEVITSDELMAHLGNCLLSIKPQEKSEGLQLNFQQNVDDAMTVLPKLATGLDVNVRFTGVSDFEYTPECSVFDLLGIPLYHGWLVDPQSPEAVRAVGKLSYNQLVERIITCKHSSDTNLVTEGLIAEQFLETTAAQLTYHGLCELTAAAKEGELSVFFRNNHFSTMTKHKSHLYLLVTDQGFLQEEQVVWESLHNVDGDSCFCDSDFHLSHSLGKGPGAEGGSGSPEKQLQVDQDYLIALSLQQQQPRGPLGLTDLELAQQLQQEEYQQQQAAQPVRMRTRVLSLQGRGATSGRPAGERRQRPKHESDCILL
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Molecular Weight
78.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FAM63A is a gene encoding a protein that is involved in various cellular processes, including cell proliferation, differentiation, and the response to stress. Recent studies have highlighted the importance of FAM63A in cancer biology, where its aberrant expression correlates with tumor progression and poor prognosis in several cancer types. The understanding of FAM63A's function has been furthered through the development of recombinant FAM63A protein, which enables researchers to study its biochemical properties and interactions with other cellular proteins. Purification of this recombinant protein allows for detailed analyses, such as examining its role in cell signaling pathways and its potential as a biomarker or therapeutic target. Additionally, investigations into the structural characteristics of FAM63A may reveal insights into its mechanism of action and how alterations in its function contribute to disease. Overall, the research on recombinant FAM63A protein is critical for elucidating its biological significance and potential implications in cancer therapy and diagnostics.
