Analytical Data
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Gene name
FAM53A
- Application
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Alternative Names
FAM53AProtein FAM53A; Dorsal neural-tube nuclear protein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6NSI3
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Expression Region
1-398aa
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AA Sequence
MVTLITEKLQ SQSLDDLTCK AEAGPLQYSA ETLNKSGRLF PLELNDQSPW KVFSGGPPVR SQAATGPDFS FLPGLSAAAH TMGLQWQPQS PRPGAGLGAA STVDPSESTG SSTAPPTKRH CRSLSEPEEL VRCRSPWRPG SSKVWTPVSK RRCDSGGSAT RQGSPGAVLP RSAVWSTGPT SPATPRPSSA SGGFVDSSEG SAGSGPLWCS AESCLPSTRR RPSLSQERLA GAGTPLPWAS SSPTSTPALG GRRGLLRCRS QPCVLSGKRS RRKRRREEDA RWTRPSLDFL KMTQTLKNSK SLCSLNYEDD DEDDTPVKTV LSSPCDSRGL PGITMPGCSQ RGLRTSPVHP NLWASRESVT SDGSRRSSGD PRDGDSVGEE GVFPRARWEL DLEQIENN
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Molecular Weight
42.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FAM53A, a member of the FAM53 gene family, has garnered attention in recent years due to its potential roles in various biological processes, including cell signaling, proliferation, and differentiation. Recent studies have suggested that FAM53A may be involved in key cellular functions and could act as a regulator in several signaling pathways, thereby influencing cellular outcomes. Its expression patterns have been linked to certain cancers and other diseases, prompting researchers to explore its functional significance further. Despite its importance, the detailed mechanisms of how FAM53A interacts with other cellular components remain poorly understood. To investigate these mechanisms, the generation of recombinant FAM53A protein has become a crucial approach. This recombinant protein can be utilized in various assays to study its biochemical properties, interaction with other proteins, and effects on cellular processes. Furthermore, understanding the structure-function relationships of FAM53A through recombinant studies could provide insights into its role in disease mechanisms. Thus, research on recombinant FAM53A holds potential for unveiling novel therapeutic targets and biomarkers, particularly in cancer research, and contributes to the broader understanding of the functions of the FAM53 family in human health and disease.
