Cat: PAX2000-12861

Recombinant Human ZNF418 Protein,His

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Analytical Data

  • Gene name

    ZNF418

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    FLJ31551; KIAA1956; MGC138449; Zinc finger Protein 418; ZN418_HUMAN; ZNF418

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q8TF45

  • Expression Region

    1-676 aa

  • AA Sequence

    MQGTVAFEDV AVNFSQEEWS LLSEVQRCLY HDVMLENWVL ISSLGCWCGS EDEEAPSKKS ISIQRVSQVS TPGAGVSPKK AHSCEMCGAI LGDILHLADH QGTHHKQKLH RCEAWGNKLY DSSNRPHQNQ YLGEKPYRSS VEEALFVKRC KFHVSEESSI FIQSGKDFLP SSGLLLQEAT HTGEKSNSKP ECESPFQWGD THYSCGECMK HSSTKHVFVQ QQRLPSREEC YCWECGKSFS KYDSVSNHQR VHTGKRPYEC GECGKSFSHK GSLVQHQRVH TGKRPYECGE CGKSFSHKGS LVQHQRVHTG ERPYECGECG KSFSQNGTLI KHQRVHTGER PYECEECGKC FTQKGNLIQH QRGHTSERPY ECEECGKCFS QKGTLTEHHR VHTRERPYEC GECGKSFSRK GHLRNHQRGH TGERPYECGE CGKSFSRKGN LIQHQRSHTG ERPYECRECR KLFRGKSHLI EHQRVHTGER PYECNECGKS FQDSSGFRVH QRVHTGEKPF ECSECGKSFP QSCSLLRHRR VHTGERPYEC GECGKSFHQS SSLLRHQKTH TAERPYECRE CGKFFSSLLE HRRVHTGERP YECRECGKTF TRRSAHFKHQ RLHTRGKPYE CSECGKSFAE TFSLTEHRRV HTGERPYECS ECGKSFHRSS SLLRHQRVHT ERSPYK

  • Molecular Weight

    77.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZNF418, a member of the zinc finger protein family, has gained attention in recent years due to its potential roles in various biological processes, including gene regulation, cell differentiation, and apoptosis. This transcription factor is characterized by the presence of multiple zinc finger motifs, which facilitate its interaction with DNA and other regulatory proteins. Studies indicate that ZNF418 may play a crucial role in development and disease, particularly in cancer, where it could influence tumor growth and metastasis. Research on ZNF418 is further motivated by its involvement in cellular stress responses and its potential as a biomarker for certain pathologies. The recombinant expression of ZNF418 protein serves as a valuable tool for elucidating its functional mechanisms, allowing researchers to investigate its structure-function relationships and regulatory networks. Understanding the biological significance of ZNF418 through recombinant protein studies could lead to novel therapeutic strategies and enhance our comprehension of its role in health and disease. Additionally, the production of ZNF418 as a recombinant protein facilitates the exploration of its interactions with other cellular components, thereby providing insights into its involvement in various signaling pathways. Hence, the investigation of ZNF418 through recombinant technologies is fundamental to advancing our knowledge in molecular biology and developing targeted interventions in related diseases.

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