Analytical Data
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Gene name
DEFb131
- Application
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Alternative Names
DEFb131；DEFB131；DEFB31；Beta-defensin 131A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P59861
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Expression Region
23-70aa
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AA Sequence
FISNDECP SEYYHCRLKC NADEHAIRYC ADFSICCKLK IIEIDGQKKW
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The DEFb131 protein, a member of the defensin family, has garnered significant attention in the field of antimicrobial research due to its potent antibacterial and antifungal properties. Defensins are small cationic peptides found in various organisms, playing a crucial role in the innate immune response. The DEFb131 variant, specifically derived from plants, exhibits unique structural characteristics that enhance its stability and activity against a broad spectrum of pathogens. Recent studies have aimed to explore its protective mechanisms, focusing on its ability to disrupt microbial membranes and modulate immune responses. The increasing prevalence of antibiotic-resistant strains has underscored the urgency to investigate alternative antimicrobial agents, positioning DEFb131 as a promising candidate for the development of new therapeutic strategies. Furthermore, research has expanded to include its applications in agriculture, where it may provide a natural solution for crop protection against phytopathogens. As such, the study of DEFb131 is pivotal not only for understanding plant defense mechanisms but also for addressing the growing challenges posed by resistant infections in both human health and agricultural sustainability.
