Analytical Data
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Gene name
ZNF395
- Application
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Alternative Names
DKFZp434K1210; HD gene regulatory region binding Protein 2; HD gene regulatory region-binding Protein 2; HD-regulating factor 2; HDBP-2; HDBP2; HDRF-2; Huntington disease gene regulatory region-binding Protein 2; Huntington's disease gene regulatory region binding Protein 2; Papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF 1; Papillomavirus-binding factor; PBF; PRF-1; PRF1; PTTG1IP; Si-1-8-14; Zinc finger Protein 395; ZN395_HUMAN; znf395
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H8N7
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Expression Region
1-513 aa
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AA Sequence
MASVLSRRLG KRSLLGARVL GPSASEGPSA APPSEPLLEG AAPQPFTTSD DTPCQEQPKE VLKAPSTSGL QQVAFQPGQK VYVWYGGQEC TGLVEQHSWM EGQVTVWLLE QKLQVCCRVE EVWLAELQGP CPQAPPLEPG AQALAYRPVS RNIDVPKRKS DAVEMDEMMA AMVLTSLSCS PVVQSPPGTE ANFSASRAAC DPWKESGDIS DSGSSTTSGH WSGSSGVSTP SPPHPQASPK YLGDAFGSPQ TDHGFETDPD PFLLDEPAPR KRKNSVKVMY KCLWPNCGKV LRSIVGIKRH VKALHLGDTV DSDQFKREED FYYTEVQLKE ESAAAAAAAA AGTPVPGTPT SEPAPTPSMT GLPLSALPPP LHKAQSSGPE HPGPESSLPS GALSKSAPGS FWHIQADHAY QALPSFQIPV SPHIYTSVSW AAAPSAACSL SPVRSRSLSF SEPQQPAPAM KSHLIVTSPP RAQSGARKAR GEAKKCRKVY GIEHRDQWCT ACRWKKACQR FLD
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Molecular Weight
54.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF395 (Zinc Finger Protein 395) is a member of the zinc finger protein family, which is known for its role in DNA binding and transcriptional regulation. Recent studies have highlighted the significance of ZNF395 in various biological processes, including cell proliferation, differentiation, and response to stress. Abnormal expression of ZNF395 has been implicated in several diseases, particularly cancer, where it may contribute to tumorigenesis through the regulation of gene expression pathways. The functional diversity of ZNF395 is largely attributed to its zinc finger motifs, which enable it to interact with specific DNA sequences and other proteins, thereby influencing various signaling pathways. Given its potential as a therapeutic target, the recombinant expression of ZNF395 has gained attention, allowing researchers to characterize its structure and function in detail. By producing recombinant ZNF395, scientists can investigate its interaction with other cellular components, providing insights into its role in health and disease. Understanding the molecular mechanisms by which ZNF395 operates can lead to the development of novel strategies for disease intervention, especially in oncology. Overall, the study of ZNF395 through recombinant protein technology offers promising avenues for elucidating its biological functions and therapeutic potential.
