Analytical Data
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基因名
ZNF395
- Application
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别名
DKFZp434K1210; HD gene regulatory region binding Protein 2; HD gene regulatory region-binding Protein 2; HD-regulating factor 2; HDBP-2; HDBP2; HDRF-2; Huntington disease gene regulatory region-binding Protein 2; Huntington's disease gene regulatory region binding Protein 2; Papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF 1; Papillomavirus-binding factor; PBF; PRF-1; PRF1; PTTG1IP; Si-1-8-14; Zinc finger Protein 395; ZN395_HUMAN; znf395
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H8N7
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表达区间
1-513 aa
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氨基酸序列
MASVLSRRLG KRSLLGARVL GPSASEGPSA APPSEPLLEG AAPQPFTTSD DTPCQEQPKE VLKAPSTSGL QQVAFQPGQK VYVWYGGQEC TGLVEQHSWM EGQVTVWLLE QKLQVCCRVE EVWLAELQGP CPQAPPLEPG AQALAYRPVS RNIDVPKRKS DAVEMDEMMA AMVLTSLSCS PVVQSPPGTE ANFSASRAAC DPWKESGDIS DSGSSTTSGH WSGSSGVSTP SPPHPQASPK YLGDAFGSPQ TDHGFETDPD PFLLDEPAPR KRKNSVKVMY KCLWPNCGKV LRSIVGIKRH VKALHLGDTV DSDQFKREED FYYTEVQLKE ESAAAAAAAA AGTPVPGTPT SEPAPTPSMT GLPLSALPPP LHKAQSSGPE HPGPESSLPS GALSKSAPGS FWHIQADHAY QALPSFQIPV SPHIYTSVSW AAAPSAACSL SPVRSRSLSF SEPQQPAPAM KSHLIVTSPP RAQSGARKAR GEAKKCRKVY GIEHRDQWCT ACRWKKACQR FLD
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分子量
54.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF395 (Zinc Finger Protein 395) is a member of the zinc finger protein family, which is known for its role in DNA binding and transcriptional regulation. Recent studies have highlighted the significance of ZNF395 in various biological processes, including cell proliferation, differentiation, and response to stress. Abnormal expression of ZNF395 has been implicated in several diseases, particularly cancer, where it may contribute to tumorigenesis through the regulation of gene expression pathways. The functional diversity of ZNF395 is largely attributed to its zinc finger motifs, which enable it to interact with specific DNA sequences and other proteins, thereby influencing various signaling pathways. Given its potential as a therapeutic target, the recombinant expression of ZNF395 has gained attention, allowing researchers to characterize its structure and function in detail. By producing recombinant ZNF395, scientists can investigate its interaction with other cellular components, providing insights into its role in health and disease. Understanding the molecular mechanisms by which ZNF395 operates can lead to the development of novel strategies for disease intervention, especially in oncology. Overall, the study of ZNF395 through recombinant protein technology offers promising avenues for elucidating its biological functions and therapeutic potential.
