Analytical Data
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Gene name
NME5
- Application
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Alternative Names
NME5;Nucleoside diphosphate kinase homolog 5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P56597
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Expression Region
1-212aa
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AA Sequence
MEISMPPPQI YVEKTLAIIK PDIVDKEEEI QDIILRSGFT IVQRRKLRLS PEQCSNFYVE KYGKMFFPNL TAYMSSGPLV AMILARHKAI SYWLELLGPN NSLVAKETHP DSLRAIYGTD DLRNALHGSN DFAAAEREIR FMFPEVIVEP IPIGQAAKDY LNLHIMPTLL EGLTELCKQK PADPLIWLAD WLLKNNPNKP KLCHHPIVEE PY
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NME5, a member of the non-metastatic 23 (NME) gene family, has garnered attention in cancer research due to its intricate role in tumor biology and metastasis. Initially identified as a protein associated with non-metastatic tissues, NME5 has been implicated in various cellular processes, including cell proliferation, differentiation, and apoptosis. Studies suggest that NME5 may influence signaling pathways that regulate these critical functions, making it a potential biomarker for cancer prognosis and a target for therapeutic intervention. Furthermore, its involvement in the cellular response to stress and its interaction with other proteins propose a multifunctional role that extends beyond tumor suppression. Understanding the molecular mechanisms underlying NME5's actions could provide insights into cancer metastasis and progression, as well as contribute to the development of novel cancer treatment strategies. As the field advances, ongoing research is focused on elucidating the comprehensive functions of NME5, its expression patterns in different cancer types, and its potential as a therapeutic target, which could pave the way for innovative approaches in oncology.











