Analytical Data
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Gene name
ZNF365
- Application
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Alternative Names
ZNF365; KIAA0844; Talanin
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q70YC4
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Expression Region
1-216 aa
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AA Sequence
MSALGQITIT VSRCWNTERN QTDKNPCLHG AYLQLRETVK NKSTHLKKPL MKQAPPWKDH LTFQPLHPAE RKTQVWRWQS GNSSDLETTS SASPWPTGSN RDVVLNTLAE SCCGLSELIT APPYAGVSIQ GFSQIWVLFP FCGGTFHHNE KDVLGLQDFE RESVSTSQSR NISLLTLGQL QNCVIGKLTI IDLLTEHLLG VRHGVICFPW GLPSSS
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Molecular Weight
24 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF365 is a member of the zinc finger protein family, which plays a crucial role in various biological processes, including gene expression regulation, cell proliferation, and apoptosis. Research surrounding ZNF365 has gained momentum due to its association with several diseases, particularly breast cancer. Studies have shown that ZNF365 functions as a transcriptional regulator, influencing the expression of genes involved in tumorigenesis and metastasis. Its potential role as a tumor suppressor has drawn attention, with evidence suggesting that ZNF365 expression levels correlate with patient outcomes, making it a potential biomarker for breast cancer prognosis. Additionally, ZNF365 has been implicated in the modulation of immune responses, further highlighting its significance in cancer biology. Researchers are particularly interested in the reconstitution of ZNF365 to gain insights into its functional mechanisms and interactions within cellular pathways. The ability to produce recombinant ZNF365 proteins allows for detailed studies on their structural properties and binding affinities, contributing to the understanding of how ZNF365 may influence cancer development and progression. This knowledge is vital for the development of targeted therapies and could lead to innovative strategies for cancer treatment. Overall, the investigation of ZNF365 and its recombinant forms represents a promising avenue in cancer research, with the potential to unveil new therapeutic targets and improve prognostic markers in oncology.
