Analytical Data
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基因名
FAM122B
- Application
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别名
DKFZp686L20116; F122B_HUMAN; Fam122b; Family with sequence similarity 122B; MGC131814; OTTHUMP00000024067; OTTHUMP00000215087; Protein FAM122B
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z309
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表达区间
1-248aa
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氨基酸序列
MAQEKMELDLEPDTSYGGTLRRSSSAPLIHGLSDLSQVFQPYTLRTRRNSTTIMSRHSLEEGLDMVNRETAHEREMQTAMQISQSWDESLSLSDSDFDKPEKLYSPKRIDFTPVSPAPSPTRGFGKMFVSSSGLPPSPVPSPRRFSSRRSQSPVKCIRPSVLGPLKRKGEMETESQPKRLFQGTTNMLSPDAAQLSDLSSCSDILDGSSSSSGLSSDPLAKGSATAESPVACSNSCSSFILMDDLSPK
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分子量
53.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
FAM122B, a member of the FAM122 family, is implicated in various cellular processes, including cell proliferation, differentiation, and response to stress. Recent research has highlighted its potential role in oncogenesis, particularly its overexpression in several cancers, suggesting that FAM122B may serve as a tumor marker or therapeutic target. Furthermore, FAM122B has been linked to key signaling pathways, such as the mTOR pathway, which is crucial for cell growth and metabolism. The recombinant protein of FAM122B is essential for investigating its molecular functions and interactions, enabling researchers to elucidate its role in cellular processes and disease mechanisms. In studies, producing recombinant FAM122B allows for the examination of its effects on cellular behavior in vitro, as well as its potential interactions with other proteins involved in signaling pathways. Understanding the biological functions and mechanisms of FAM122B not only contributes to the fundamental knowledge of cellular biology but also has significant implications for developing novel therapeutic strategies for cancers and other diseases where FAM122B is dysregulated. As research progresses, the characterization of the FAM122B protein could lead to insights into its functions and open new avenues for targeted therapies, underlining the importance of continued investigation into this intriguing protein.
