Analytical Data
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Gene name
ZNF278
- Application
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Alternative Names
8430401L15Rik; AI447519; and zinc finger-containing Protein 1; AT hook-; BTB POZ domain zinc finger transcription factor; BTB/POZ domain zinc finger transcription factor; dJ400N23; Mazr; PATZ ; PATZ1; PATZ1_HUMAN; POZ (BTB) and AT hook containing zinc finger 1; POZ . AT hook. and zinc finger containing Protein 1; POZ-; Protein kinase A RI subunit alpha associated Protein; Protein kinase A RI subunit alpha-associated Protein; RIAZ; Transcription factor MAZR ; ZBTB19; Zfp278; Zinc finger and BTB domain containing Protein 19 ; Zinc finger and BTB domain-containing Protein 19; Zinc finger Protein 278; Zinc finger Protein 278. isoform CRA_d; Zinc finger sarcoma gene Protein; ZNF278; ZSG
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HBE1
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Expression Region
1-687 aa
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AA Sequence
MERVNDASCG PSGCYTYQVS RHSTEMLHNL NQQRKNGGRF CDVLLRVGDE SFPAHRAVLA ACSEYFESVF SAQLGDGGAA DGGPADVGGA TAAPGGGAGG SRELEMHTIS SKVFGDILDF AYTSRIVVRL ESFPELMTAA KFLLMRSVIE ICQEVIKQSN VQILVPPARA DIMLFRPPGT SDLGFPLDMT NGAALAANSN GIAGSMQPEE EAARAAGAAI AGQASLPVLP GVDRLPMVAG PLSPQLLTSP FPSVASSAPP LTGKRGRGRP RKANLLDSMF GSPGGLREAG ILPCGLCGKV FTDANRLRQH EAQHGVTSLQ LGYIDLPPPR LGENGLPISE DPDGPRKRSR TRKQVACEIC GKIFRDVYHL NRHKLSHSGE KPYSCPVCGL RFKRKDRMSY HVRSHDGSVG KPYICQSCGK GFSRPDHLNG HIKQVHTSER PHKCQTCNAS FATRDRLRSH LACHEDKVPC QVCGKYLRAA YMADHLKKHS EGPSNFCSIC NRGFSSASYL KVHVKTHHGV PLPQVSRHQE PILNGGAAFH CARTYGNKEG QKCSHQDPIE SSDSYGDLSD ASDLKTPEKQ SANGSFSCDM AVPKNKMESD GEKKYPCPEC GSFFRSKSYL NKHIQKVHVR ALGGPLGDLG PALGSPFSPQ QNMSLLESFG FQIVQSAFAS SLVDPEVDQQ PMGPEGK
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Molecular Weight
74 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZNF278, a member of the zinc finger protein family, has gained attention in the field of molecular biology due to its potential roles in transcriptional regulation and its involvement in various cellular processes. This protein is characterized by its zinc finger motifs, which facilitate DNA binding and interactions with other proteins, thereby influencing gene expression. Previous studies indicate that ZNF278 may play a crucial role in development and differentiation, particularly in the context of stem cells and immune responses. However, the precise mechanisms of action and the specific target genes regulated by ZNF278 are not fully understood. The study of recombinant ZNF278 is vital for elucidating its biological functions and understanding its potential implications in diseases such as cancer, where dysregulation of zinc finger proteins is often observed. Producing recombinant ZNF278 allows for in vitro analyses, including binding assays and functional studies, providing insights into its role in cellular signaling pathways. Moreover, characterizing the protein's structure and interactions could reveal novel therapeutic targets and strategies for modulating its function in pathological conditions. Overall, the investigation of ZNF278 through recombinant protein technology represents a promising avenue for advancing our understanding of gene regulation and developing innovative approaches to treat diseases associated with its dysregulation.
