Cat: PAX2000-12037

Recombinant Human TMEM39A Protein,GST

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Analytical Data

  • Gene name

    TMEM39A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    TMEM39ATransmembrane Protein 39A

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NV64

  • Expression Region

    1-488 aa

  • AA Sequence

    MPGGRRGPSRQQLSRSALPSLQTLVGGGCGNGTGLRNRNGSAIGLPVPPITALITPGPVRHCQIPDLPVDGSLLFEFLFFIYLLVALFIQYINIYKTVWWYPYNHPASCTSLNFHLIDYHLAAFITVMLARRLVWALISEATKAGAASMIHYMVLISARLVLLTLCGWVLCWTLVNLFRSHSVLNLLFLGYPFGVYVPLCCFHQDSRAHLLLTDYNYVVQHEAVEESASTVGGLAKSKDFLSLLLESLKEQFNNATPIPTHSCPLSPDLIRNEVECLKADFNHRIKEVLFNSLFSAYYVAFLPLCFVKSTQYYDMRWSCEHLIMVWINAFVMLTTQLLPSKYCDLLHKSAAHLGKWQKLEHGSYSNAPQHIWSENTIWPQGVLVRHSRCLYRAMGPYNVAVPSDVSHARFYFLFHRPLRLLNLLILIEGSVVFYQLYSLLRSEKWNHTLSMALILFCNYYVLFKLLRDRIVLGRAYSYPLNSYELKAN

  • Molecular Weight

    82.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TMEM39A (Transmembrane Protein 39A) is a gene that encodes a protein implicated in several cellular processes, including endosomal trafficking, cellular stress response, and regulation of ion homeostasis. Research has indicated that TMEM39A plays a crucial role in modulating the functions of lysosomes and endosomes, which are vital for cellular digestion and waste recycling. Its involvement in these pathways suggests potential links to various diseases, including neurodegenerative disorders and cancer. Recent studies have focused on the expression and functional characterization of TMEM39A recombinant proteins to better understand its biological roles and mechanisms. By producing TMEM39A as a recombinant protein, researchers aim to elucidate its structure-function relationships and interactions with other cellular components. This research not only aids in uncovering the basic molecular biology behind TMEM39A but may also pave the way for developing therapeutic strategies targeting TMEM39A-related pathways in disease contexts. Thus, the study of TMEM39A recombinant proteins represents a promising avenue for advancing biomedical knowledge and therapeutic applications.

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