Cat: PAX2000-12762

Recombinant Human ZNF19 Protein,His

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Analytical Data

  • Gene name

    ZNF19

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    KOX12; zinc finger Protein 19 (KOX 12); Zinc finger Protein 19; Zinc finger Protein KOX12; ZNF19; ZNF19_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P17023

  • Expression Region

    1-458 aa

  • AA Sequence

    MAAMPLKAQY QEMVTFEDVA VHFTKTEWTG LSPAQRALYR SVMLENFGNL TALGYPVPKP ALISLLERGD MAWGLEAQDD PPAERTKNVC KDVETNIDSE STLIQGISEE RDGMMSHGQL KSVPQRTDFP ETRNVEKHQD IPTVKNIQGK VPRIPCARKP FICEECGKSF SYFSYYARHQ RIHTGEKPFE CSECGKAFNG NSSLIRHQRI HTGERPYQCE ECGRAFNDNA NLIRHQRIHS GDRPYYCTEC GNSFTSSSEF VIHQRIHTGE KPYECNECGK AFVGNSPLLR HQKIHTGEKP YECNECGKSF GRTSHLSQHQ RIHTGEKPYS CKVCGQAFNF HTKLTRHQRI HSEEKPFDCV DCGKAFSAQE QLKRHLRIHT QESSYVCDEC GKALTSKRNL HQHQRIHTGE KPYECSKYEK AFGTSSQLGH LEHVYSGEKP VLDICRFGLP EFFTPFYW

  • Molecular Weight

    52.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ZNF19 is a member of the zinc finger protein family, which plays a crucial role in transcriptional regulation and is implicated in various biological processes, including cell differentiation, proliferation, and apoptosis. This gene is of particular interest due to its potential involvement in cancer development and progression, as alterations in its expression have been linked to several types of tumors. The study of recombinant ZNF19 proteins is essential for understanding the molecular mechanisms underlying its function and regulation. Recombinant protein expression systems allow for the production of ZNF19 in a controlled environment, facilitating the investigation of its structure-function relationship and interactions with other cellular components. Furthermore, elucidating the role of ZNF19 in gene regulation can provide insights into its potential as a therapeutic target. Current research is focused on characterizing the biochemical properties of ZNF19, including its DNA-binding capabilities and the identification of its target genes. By employing techniques such as chromatin immunoprecipitation and functional assays, researchers aim to reveal the pathway by which ZNF19 modulates gene expression in normal and pathological conditions. Overall, the study of recombinant ZNF19 is significant for advancing our understanding of its biological functions and its implications in disease, particularly in oncology, and could lead to the development of novel diagnostic and therapeutic strategies.

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