Analytical Data
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基因名
ZNF19
- Application
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别名
KOX12; zinc finger Protein 19 (KOX 12); Zinc finger Protein 19; Zinc finger Protein KOX12; ZNF19; ZNF19_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P17023
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表达区间
1-458 aa
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氨基酸序列
MAAMPLKAQY QEMVTFEDVA VHFTKTEWTG LSPAQRALYR SVMLENFGNL TALGYPVPKP ALISLLERGD MAWGLEAQDD PPAERTKNVC KDVETNIDSE STLIQGISEE RDGMMSHGQL KSVPQRTDFP ETRNVEKHQD IPTVKNIQGK VPRIPCARKP FICEECGKSF SYFSYYARHQ RIHTGEKPFE CSECGKAFNG NSSLIRHQRI HTGERPYQCE ECGRAFNDNA NLIRHQRIHS GDRPYYCTEC GNSFTSSSEF VIHQRIHTGE KPYECNECGK AFVGNSPLLR HQKIHTGEKP YECNECGKSF GRTSHLSQHQ RIHTGEKPYS CKVCGQAFNF HTKLTRHQRI HSEEKPFDCV DCGKAFSAQE QLKRHLRIHT QESSYVCDEC GKALTSKRNL HQHQRIHTGE KPYECSKYEK AFGTSSQLGH LEHVYSGEKP VLDICRFGLP EFFTPFYW
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分子量
52.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF19 is a member of the zinc finger protein family, which plays a crucial role in transcriptional regulation and is implicated in various biological processes, including cell differentiation, proliferation, and apoptosis. This gene is of particular interest due to its potential involvement in cancer development and progression, as alterations in its expression have been linked to several types of tumors. The study of recombinant ZNF19 proteins is essential for understanding the molecular mechanisms underlying its function and regulation. Recombinant protein expression systems allow for the production of ZNF19 in a controlled environment, facilitating the investigation of its structure-function relationship and interactions with other cellular components. Furthermore, elucidating the role of ZNF19 in gene regulation can provide insights into its potential as a therapeutic target. Current research is focused on characterizing the biochemical properties of ZNF19, including its DNA-binding capabilities and the identification of its target genes. By employing techniques such as chromatin immunoprecipitation and functional assays, researchers aim to reveal the pathway by which ZNF19 modulates gene expression in normal and pathological conditions. Overall, the study of recombinant ZNF19 is significant for advancing our understanding of its biological functions and its implications in disease, particularly in oncology, and could lead to the development of novel diagnostic and therapeutic strategies.
