Analytical Data
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基因名
EPS8L3
- Application
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别名
EPS8L3; EPS8R3Epidermal growth factor receptor kinase substrate 8-like protein 3; EPS8-like protein 3; Epidermal growth factor receptor pathway substrate 8-related protein 3; EPS8-related protein 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TE67
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表达区间
1-594aa
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氨基酸序列
MSRPSSRAIYLHRKEYSQNLTSEPTLLQHRVEHLMTCKQGSQRVQGPEDALQKLFEMDAQGRVWSQDLILQVRDGWLQLLDIETKEELDSYRLDSIQAMNVALNTCSYNSILSITVQEPGLPGTSTLLFQCQEVGAERLKTSLQKALEEELEQSRPRLGGLQPGQDRWRGPAMERPLPMEQARYLEPGIPPEQPHQRTLEHSLPPSPRPLPRHTSAREPSAFTLPPPRRSSSPEDPERDEEVLNHVLRDIELFMGKLEKAQAKTSRKKKFGKKNKDQGGLTQAQYIDCFQKIKYSFNLLGRLATWLKETSAPELVHILFKSLNFILARCPEAGLAAQVISPLLTPKAINLLQSCLSPPESNLWMGLGPAWTTSRADWTGDEPLPYQPTFSDDWQLPEPSSQAPLGYQDPVSLRRGSHRLGSTSHFPQEKTHNHDPQPGDPNSRPSSPKPAQPALKMQVLYEFEARNPRELTVVQGEKLEVLDHSKRWWLVKNEAGRSGYIPSNILEPLQPGTPGTQGQSPSRVPMLRLSSRPEEVTDWLQAENFSTATVRTLGSLTGSQLLRIRPGELQMLCPQEAPRILSRLEAVRRMLGISP
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分子量
93.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
EPS8L3, a member of the EPS8 protein family, is known for its role in actin cytoskeleton dynamics, signal transduction, and cellular motility. The interest in EPS8L3 has surged due to its potential implications in various biological processes and diseases, particularly in cancer progression and metastasis. Research has shown that EPS8L3 is involved in the regulation of cell shape, migration, and adhesion, which are critical in tumor development and invasion. Studies have demonstrated that alterations in EPS8L3 expression can influence tumor cell behavior, making it a candidate for targeted cancer therapies. Furthermore, the protein's interaction with other cellular components, such as receptors and other signaling molecules, suggests that it plays a pivotal role in mediating extracellular signals that affect cell proliferation and survival. Understanding the molecular mechanisms underlying EPS8L3 function could unveil new therapeutic opportunities and biomarkers for cancer diagnosis and prognosis. As a result, the production of recombinant EPS8L3 protein has become a focal point of research, enabling scientists to investigate its structure, function, and potential as a drug target. This research endeavors to elucidate the precise biochemical pathways mediated by EPS8L3, contributing to the broader understanding of its role in both normal physiology and disease states. Overall, the study of EPS8L3 serves as an important step in uncovering the complexities of cell signaling and potential intervention strategies in cancer treatment.
