Analytical Data
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Gene name
THUMPD3
- Application
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Alternative Names
THUM3_HUMAN; THUMP domain containing 3; THUMP domain-containing Protein 3; THUMPD3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BV44
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Expression Region
1-507 aa
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AA Sequence
MCDIEEATNQ LLDVNLHENQ KSVQVTESDL GSESELLVTI GATVPTGFEQ TAADEVREKL GSSCKISRDR GKIYFVISVE SLAQVHCLRS VDNLFVVVQE FQDYQFKQTK EEVLKDFEDL AGKLPWSNPL KVWKINASFK KKKAKRKKIN QNSSKEKINN GQEVKIDQRN VKKEFTSHAL DSHILDYYEN PAIKEDVSTL IGDDLASCKD ETDESSKEET EPQVLKFRVT CNRAGEKHCF TSNEAARDFG GAVQDYFKWK ADMTNFDVEV LLNIHDNEVI VGIALTEESL HRRNITHFGP TTLRSTLAYG MLRLCDPLPY DIIVDPMCGT GAIPIEGATE WSDCFHIAGD NNPLAVNRAA NNIASLLTKS QIKEGKPSWG LPIDAVQWDI CNLPLRTGSV DIIVTDLPFG KRMGSKKRNW NLYPACLREM SRVCTPTTGR AVLLTQDTKC FTKALSGMRH VWRKVDTVWV NVGGLRAAVY VLIRTPQAFV HPSEQDGERG TLWQCKE
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Molecular Weight
57.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THUMPD3 is a member of the THUMP (THoughtful and Unified Metabolic Pathways) domain-containing protein family, which plays a crucial role in various biological processes, including RNA metabolism and regulation. The study of THUMPD3 has gained importance due to its potential involvement in cellular stress responses and its association with neurodegenerative diseases. Recent research has highlighted the significance of THUMPD3 in modulating the stress response pathways, particularly under conditions of oxidative stress, suggesting that it may act as a protective agent for cellular integrity. Additionally, its unique structural features, such as the presence of specific motifs allowing for interaction with RNA and other proteins, make THUMPD3 a fascinating target for exploring mechanisms of gene regulation and expression. Understanding the functional roles and mechanisms of THUMPD3 could provide insights into how cells cope with environmental stressors and may unveil novel strategies for therapeutic interventions in diseases where these pathways are disrupted. Thus, research on THUMPD3, including its recombinant protein studies, aims to elucidate its biological functions, interaction partners, and the implications of its activity in cellular contexts, contributing to the broader understanding of cellular resilience and pathogenesis.
