Analytical Data
-
基因名
THUMPD2
- Application
-
别名
THUMPD2; C2orf8; THUMP domain-containing Protein 2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BTF0
-
表达区间
1-503 aa
-
氨基酸序列
MSEARGEPGS GPEAGARFFC TAGRGLEPFV MREVRARLAA TQVEYISGKV FFTTCSDLNM LKKLKSAERL FLLIKKQFPL IISSVSKGKI FNEMQRLINE DPGSWLNAIS IWKNLLELDA KKEKLSQRDD NQLKRKVGEN EIIAKKLKIE QMQKIEENRD CQLEKQIKEE TLEQRDFTTK SEKFQEEEFQ NDIEKAIDTH NQNDLTFRVS CRCSGTIGKA FTAQEVGKVI GIAIMKHFGW KADLRNPQLE IFIHLNDIYS VVGIPVFRVS LASRAYIKTA GLRSTIAWAM ASLADIKAGA FVLDPMCGLG TILLEAAKEW PDVYYVGADV SDSQLLGTWD NLKAAGLEDK IELLKISVIE LPLPSESVDI IISDIPFGKK FKLGKDIKSI LQEMERVLHV GGTIVLLLSE DHHRRLTDCK ESNIPFNSKD SHTDEPGIKK CLNPEEKTGA FKTASTSFEA SNHKFLDRMS PFGSLVPVEC YKVSLGKTDA FICKYKKSHS SGL
-
分子量
56.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THUMPD2, a member of the THUMP domain-containing protein family, has garnered attention in recent years due to its potential roles in various cellular processes, including RNA metabolism and mitochondrial function. Initial studies suggest that THUMPD2 is involved in the regulation of gene expression and may act as a critical player in the stress response pathways within cells. Its unique structure, featuring a conserved THUMP domain, indicates a possible interaction with RNA molecules, which could implicate THUMPD2 in RNA stability and processing. Emerging research highlights its significance in maintaining cellular integrity under stress conditions, making it a candidate for further investigation in the context of diseases characterized by dysregulated RNA metabolism, such as cancer and neurodegenerative disorders. The recombinant production of THUMPD2 allows for detailed biochemical and structural studies, aiding in the elucidation of its functions and potential regulatory mechanisms. Understanding the role of THUMPD2 is crucial for unraveling its contributions to cellular homeostasis and its implications in pathological states, positioning it as a promising target for therapeutic intervention in RNA-related diseases.
