Analytical Data
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Gene name
THNSL1
- Application
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Alternative Names
THNS1_HUMAN; THNSL1; Threonine synthase-like 1; TSH1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IYQ7
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Expression Region
1-743 aa
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AA Sequence
MLHFNRCHHL KKITQKCFSS IHVKTDKHAQ RFLSRTFALA ELRKSWYSTH SLVGDKNIIL MGPPGAGKTT VGRIIGQKLG CCVIDVDDDI LEKTWNMSVS EKLQDVGNEQ FLEEEGKAVL NFSASGSVIS LTGSNPMHDA SMWHLKKNGI IVYLDVPLLD LICRLKLMKT DRIVGQNSGT SMKDLLKFRR QYYKKWYDAR VFCESGASPE EVADKVLNAI KRYQDVDSET FISTRHVWPE DCEQKVSAKF FSEAVIEGLA SDGGLFVPAK EFPKLSCGEW KSLVGATYVE RAQILLERCI HPADIPAARL GEMIETAYGE NFACSKIAPV RHLSGNQFIL ELFHGPTGSF KDLSLQLMPH IFAHCIPPSC NYMILVATSG DTGSAVLNGF SRLNKNDKQR IAVVAFFPEN GVSDFQKAQI IGSQRENGWA VGVESDFDFC QTAIKRIFND SDFTGFLTVE YGTILSSANS INWGRLLPQV VYHASAYLDL VSQGFISFGS PVDVCIPTGN FGNILAAVYA KMMGIPIRKF ICASNQNHVL TDFIKTGHYD LRERKLAQTF SPSIDILKSS NLERHLHLMA NKDGQLMTEL FNRLESQHHF QIEKALVEKL QQDFVADWCS EGECLAAINS TYNTSGYILD PHTAVAKVVA DRVQDKTCPV IISSTAHYSK FAPAIMQALK IKEINETSSS QLYLLGSYNA LPPLHEALLE RTKQQEKMEY QVCAADMNVL KSHVEQLVQN QFI
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Molecular Weight
83.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THNSL1, or Threonine Synthase-like 1, is a protein that has garnered increasing attention in the field of molecular biology and genetics due to its potential roles in cellular metabolism and regulatory processes. As a member of the threonine synthase family, THNSL1 is believed to participate in the synthesis of essential amino acids and the metabolism of various biomolecules. Its expression levels and functional dynamics in different tissues suggest a pivotal role in biological pathways that are crucial for growth and development. Recent studies have indicated that alterations in THNSL1 expression may be associated with various diseases, including metabolic disorders and cancers, highlighting its significance in health and disease contexts. Researchers are focusing on recombinant protein techniques to produce and characterize THNSL1, allowing for a deeper understanding of its structure-function relationships and interactions with other molecular players. The exploration of THNSL1’s biochemical properties and its involvement in signaling cascades could pave the way for novel therapeutic strategies targeting metabolic diseases. By employing advanced methodologies such as CRISPR gene editing and high-throughput screening, scientists aim to elucidate the exact roles of THNSL1 in human physiology and pathology, thereby enhancing our comprehension of its biological importance and potential as a drug target. The ongoing research into THNSL1 is expected to unravel new insights into metabolic regulation, potentially leading to innovative approaches in disease management and therapeutic interventions.
