Analytical Data
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Gene name
THAP10
- Application
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Alternative Names
THA10_HUMAN; THAP 10; THAP domain containing 10; THAP domain-containing Protein 10; THAP10
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9P2Z0
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Expression Region
1-257 aa
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AA Sequence
MPARCVAAHC GNTTKSGKSL FRFPKDRAVR LLWDRFVRGC RADWYGGNDR SVICSDHFAP ACFDVSSVIQ KNLRFSQRLR LVAGAVPTLH RVPAPAPKRG EEGDQAGRLD TRGELQAARH SEAAPGPVSC TRPRAGKQAA ASQITCENEL VQTQPHADNP SNTVTSVPTH CEEGPVHKST QISLKRPRHR SVGIQAKVKA FGKRLCNATT QTEELWSRTS SLFDIYSSDS ETDTDWDIKS EQSDLSYMAV QVKEETC
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Molecular Weight
28.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
THAP10, a member of the THAP (THAP domain containing) protein family, has garnered increasing attention in the field of molecular biology due to its potential role in various cellular processes, including transcriptional regulation and developmental biology. Initially identified as a transcription factor, THAP10 is characterized by the presence of a highly conserved THAP domain that facilitates DNA binding and interaction with other proteins. Its expression has been linked to key developmental stages and it has been implicated in the regulation of genes associated with cell proliferation and differentiation. Research has indicated that THAP10 may play critical roles in specific physiological processes such as hematopoiesis and stem cell function, making it a focus for studies exploring genetic regulation and cellular mechanisms underlying these processes. Furthermore, dysregulation of THAP10 expression has been associated with certain pathological conditions, including cancer. Consequently, understanding the structure, function, and regulatory mechanisms of THAP10 could provide valuable insights into its biological significance, offering potential avenues for therapeutic intervention. Therefore, the production and characterization of recombinant THAP10 protein is essential for in-depth functional studies, enabling researchers to unravel its roles in cellular signaling pathways, gene expression regulation, and its implications in diseases. Such investigations could pave the way for novel strategies in treating conditions linked to THAP10 dysregulation, highlighting the importance of this protein in both basic and applied biomedical research.
