Analytical Data
-
基因名
ZDHHC4
- Application
-
别名
Zinc finger DHHC domain-containing Protein 4; Zinc finger Protein 374; ZNF374
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9NPG8
-
表达区间
1-344 aa
-
氨基酸序列
MDFLVLFLFYLASVLMGLVLICVCSKTHSLKGLARGGAQIFSCIIPECLQRAVHGLLHYLFHTRNHTFIVLHLVLQGMVYTEYTWEVFGYCQELELSLHYLLLPYLLLGVNLFFFTLTCGTNPGIITKANELLFLHVYEFDEVMFPKNVRCSTCDLRKPARSKHCSVCNWCVHRFDHHCVWVNNCIGAWNIRYFLIYVLTLTASAATVAIVSTTFLVHLVVMSDLYQETYIDDLGHLHVMDTVFLIQYLFLTFPRIVFMLGFVVVLSFLLGGYLLFVLYLAATNQTTNEWYRGDWAWCQRCPLVAWPPSAEPQVHRNIHSHGLRSNLQEIFLPAFPCHERKKQE
-
分子量
66.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZDHHC4 (Zinc Finger DHHC-Type Palmitoyltransferase 4) is an enzyme that plays a crucial role in the post-translational modification of proteins through palmitoylation, a process that adds palmitic acid groups to cysteine residues. This modification is significant for the regulation of protein localization, stability, and function, influencing various cellular processes including signal transduction and membrane dynamics. Dysregulation of palmitoylation is linked to several diseases, including cancer and neurodegenerative disorders. Research on ZDHHC4 has garnered attention due to its specific involvement in the palmitoylation of critical signaling proteins and its potential implications in cellular signaling pathways. Understanding the structure and function of ZDHHC4 can provide insights into the mechanisms underlying these diseases and identify new therapeutic targets. Recent studies have focused on the recombinant expression of ZDHHC4 to investigate its enzymatic activity and substrate specificity, facilitating a more in-depth exploration of its role in cellular functions. This research not only enhances our understanding of ZDHHC4 but also contributes to the broader field of protein modification, offering potential avenues for therapeutic interventions in diseases associated with aberrant palmitoylation.
