Analytical Data
-
基因名
ZBTB12
- Application
-
别名
ZBTB12; C6orf46; G10; NG35; Zinc finger and BTB domain-containing Protein 12; Protein G10
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9Y330
-
表达区间
1-459 aa
-
氨基酸序列
MASGVEVLRFQLPGHEAATLRNMNQLRAEERFCDVTIVADSLKFRGHKVILAACSPFLRDQFLLNPSSELQVSLMHSARIVADLLLSCYTGALEFAVRDIVNYLTAASYLQMEHVVEKCRNALSQFIEPKIGLKEDGVSEASLVSSISATKSLLPPARTPKPAPKPPPPPPLPPPLLRPVKLEFPLDEDLELKAEEEDEDEDEDVSDICIVKVESALEVAHRLKPPGGLGGGLGIGGSVGGHLGELAQSSVPPSTVAPPQGVVKACYSLSEDAEGEGLLLIPGGRASVGATSGLVEAAAVAMAARGAGGSLGAGGSRGPLPGGFSGGNPLKNIKCTKCPEVFQGVEKLVFHMRAQHFIFMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGICGKCFTQKSTLHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQHGKTTAENVLEASVAEINVLIR
-
分子量
75.5 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZBTB12, also known as ZNF599, is a member of the zinc finger and BTB (Bric-a-brac, Tramtrack, and Bric-a-brac) domain-containing protein family, which plays crucial roles in various biological processes, including transcriptional regulation, cell differentiation, and immune responses. Research on ZBTB12 has gained traction due to its implications in cancer biology, where it has been identified as a potential tumor suppressor gene and a key player in the regulation of cell proliferation and apoptosis. The protein's ability to modulate gene expression via its interaction with chromatin and other transcriptional factors makes it an attractive target for therapeutic investigations. Moreover, its involvement in inflammatory responses and immune regulation suggests a broader role in cellular homeostasis and disease pathology. Understanding ZBTB12's functions through the development of recombinant protein models enables researchers to elucidate its mechanistic pathways and interactions with other cellular components. The recombinant ZBTB12 protein could facilitate studies aimed at exploring its structural characteristics, post-translational modifications, and potential as a biomarker or therapeutic target in various diseases, particularly in oncology and immunology. Recent advancements in recombinant DNA technology and protein expression systems have paved the way for harnessing ZBTB12 for further studies, aiming to unlock its potential in clinical applications and provide insights into the molecular underpinnings of diseases associated with its dysregulation. This research is crucial for developing targeted therapies that could improve patient outcomes in cancer and other disorders related to the immune system.












