Analytical Data
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基因名
TAOK1
- Application
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别名
2810468K05Rik; AU020252; D130018F14Rik; EC 2.7.11.1; FLJ14314; hKFC B; hKFC-B; KIAA1361; Kinase from chicken homolog B; MAP3K16; MARK kinase; MARKK; MGC29021; Microtubule affinity regulating kinase kinase; mKIAA1361; Prostate-derived sterile 20-like kinase 2; PSK2; Serine/threonine kinase TAO1; Serine/threonine protein kinase TAO1 ; Serine/threonine protein kinase TAO1 homolog; Serine/threonine-protein kinase TAO1; STE20 like kinase ; STE20 like kinase PSK2 ; STE20-like kinase PSK2; TAO kinase 1; Taok1; TAOK1_HUMAN; Thousand and one amino acid protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7L7X3
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表达区间
892-1001 aa
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氨基酸序列
LSNLSPEAFSHSYPGASGWSHNPTGGPGPHWGHPMGGPPQAWGHPMQGGPQPWGHPSGPMQGVPRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT
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分子量
37.84kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TAOK1 (TAO Kinase 1) is a serine/threonine kinase that plays a pivotal role in various cellular processes, including cell growth, differentiation, and apoptosis. It is part of the TAO family of kinases that are known to be activated by the presence of Rho GTPases, which are critical regulators of the cytoskeleton and cellular signaling pathways. Research has indicated that TAOK1 is involved in the development of neurodegenerative diseases and certain types of cancer, making it a significant target for therapeutic intervention. Moreover, studies suggest that TAOK1 may influence neuronal survival and stress response mechanisms, further establishing its importance in neurobiology. The investigation of TAOK1 recombinant proteins provides valuable insights into its functional properties, molecular interactions, and potential roles in pathological conditions. Understanding the structure-function relationship of TAOK1 through intensive research may not only elucidate its mechanism of action but also pave the way for novel drug development aimed at modulating its activity in disease contexts. As such, recombinant TAOK1 proteins serve as essential tools for studying its biological functions and therapeutic implications.












