Analytical Data
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基因名
TA-NFKBH
- Application
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别名
NFKBID; IKBNS; NF-kappa-B inhibitor delta; I-kappa-B-delta; IkB-delta; IkappaBdelta; IkappaBNS; T-cell activation NFKB-like protein; TA-NFKBH
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NI38
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表达区间
1-313 aa
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氨基酸序列
MEAGPWRVSA PPSGPPQFPA VVPGPSLEVA RAHMLALGPQ QLLAQDEEGD TLLHLFAARG LRWAAYAAAE VLQVYRRLDI REHKGKTPLL VAAAANQPLI VEDLLNLGAE PNAADHQGRS VLHVAATYGL PGVLLAVLNS GVQVDLEARD FEGLTPLHTA ILALNVAMRP SDLCPRVLST QARDRLDCVH MLLQMGANHT SQEIKSNKTV LHLAVQAANP TLVQLLLELP RGDLRTFVNM KAHGNTALHM AAALPPGPAQ EAIVRHLLAA GADPTLRNLE NEQPVHLLRP GPGPEGLRQL LKRSRVAPPG LSS
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分子量
33.4kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TA-NFKBH is a recombinant protein that has garnered interest in the field of molecular biology and immunology due to its potential role in modulating the immune response. The NF-kB signaling pathway is critical in regulating the expression of various genes involved in inflammation, immune responses, and cell survival. Abnormal regulation of NF-kB is associated with numerous diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. Researchers have focused on TA-NFKBH protein because it serves as a key inhibitor of this pathway, making it a valuable tool for studying its dynamics and interactions. Understanding the structure and function of TA-NFKBH can provide insights into therapeutic strategies aimed at regulating NF-kB activity, thus opening new avenues for treatment in diseases where this pathway is dysregulated. Furthermore, the development of TA-NFKBH as a recombinant protein allows for high-yield production and detailed characterization, facilitating both basic research and potential clinical applications. As a result, ongoing studies aim to elucidate the biochemical mechanisms involved and assess its efficacy in preclinical models, with hopes of advancing our understanding of NF-kB-related pathologies and enhancing immunotherapeutic approaches.
