Analytical Data
-
基因名
DPF2
- Application
-
别名
Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4; D4 zinc and double PHD fingers family 2; Double PHD fingers 2; double PHD fingers family 2; DPF 2; DPF2; MGC10180; Protein requiem; REQ; REQU_HUMAN
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q92785
-
表达区间
1-391aa
-
氨基酸序列
MAAVVENVVKLLGEQYYKDAMEQCHNYNARLCAERSVRLPFLDSQTGVAQSNCYIWMEKRHRGPGLASGQLYSYPARRWRKKRRAHPPEDPRLSFPSIKPDTDQTLKKEGLISQDGSSLEALLRTDPLEKRGAPDPRVDDDSLGEFPVTNSRARKRILEPDDFLDDLDDEDYEEDTPKRRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHYAHSHLAEEEGEDKEDSQPPTPVSQRSEEQKSKKGPDGLALPNNYCDFCLGDSKINKKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHMYCLTPSMSEPPEGSWSCHLCLDLLKEKASIYQNQNSS
-
分子量
68.64 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DPM1 (Dolichyl-Phosphate Mannosyltransferase 1) is a crucial enzyme involved in the N-glycosylation process, which is essential for the proper folding, stability, and function of numerous glycoproteins. This enzyme catalyzes the transfer of mannose residues from dolichol phosphate to nascent glycoprotein chains, forming mannose-rich glycan structures that serve as key determinants for protein maturation and cellular signaling. Mutations in the DPM1 gene have been linked to genetic disorders such as Congenital Disorder of Glycosylation (CDG), which can lead to severe multi-organ dysfunction and developmental issues. Due to its pivotal role in glycosylation, DPM1 is a target of interest for both basic research and therapeutic applications. Understanding the structure and function of DPM1 can provide insights into the mechanisms of protein glycosylation and unveil potential intervention strategies for related diseases. Additionally, the production of recombinant DPM1 protein allows for the exploration of its enzymatic activity, substrate specificity, and interaction with other glycosylation pathway components. This research is significant for developing diagnostic tools and novel treatments for glycosylation disorders, ultimately aiming to enhance patient outcomes in affected individuals.
