Analytical Data
-
基因名
SSBP3
- Application
-
别名
SSBP3; SSDP; SSDP1Single-stranded DNA-binding Protein 3; Sequence-specific single-stranded-DNA-binding Protein
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BWW4
-
表达区间
1-388 aa
-
氨基酸序列
MFAKGKGSAV PSDGQAREKL ALYVYEYLLH VGAQKSAQTF LSEIRWEKNI TLGEPPGFLH SWWCVFWDLY CAAPERRDTC EHSSEAKAFH DYSAAAAPSP VLGNIPPNDG MPGGPIPPGF FQGPPGSQPS PHAQPPPHNP SSMMGPHSQP FMSPRYAGGP RPPIRMGNQP PGGVPGTQPL LPNSMDPTRQ QGHPNMGGSM QRMNPPRGMG PMGPGPQNYG SGMRPPPNSL GPAMPGINMG PGAGRPWPNP NSANSIPYSS SSPGTYVGPP GGGGPPGTPI MPSPADSTNS SDNIYTMINP VPPGGSRSNF PMGPGSDGPM GGMGGMEPHH MNGSLGSGDI DGLPKNSPNN ISGISNPPGT PRDDGELGGN FLHSFQNDNY SPSMTMSV
-
分子量
40.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SSBP3 (Single-stranded DNA Binding Protein 3) is a crucial component in the regulation of DNA metabolism, playing significant roles in processes such as DNA replication, repair, and recombination. The protein is known to interact with single-stranded DNA, stabilizing it and preventing secondary structure formation which could impede essential cellular functions. Recent studies have highlighted its involvement in mitochondrial DNA maintenance and its potential implications in various disorders, such as cancers and mitochondrial dysfunction syndromes. As research progresses, the functional characterization of SSBP3 has become paramount, particularly the understanding of its structural properties, binding affinities, and interaction mechanisms with nucleic acids. This necessitates the production of recombinant SSBP3 proteins, which can be utilized in biochemical assays to elucidate these properties further. The generation of these proteins often involves the use of heterologous expression systems, allowing researchers to obtain large quantities of purified SSBP3 for in-depth studies. By exploring the functional and structural nuances of SSBP3, scientists aim to unravel its contributions to genomic stability, cellular health, and the molecular underpinnings of diseases associated with its dysfunction. The growing body of research surrounding SSBP3 not only fosters a deeper understanding of DNA binding proteins but also indicates potential therapeutic targets for interventions in genomic instability-related pathologies.
