Analytical Data
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基因名
DLEU1
- Application
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别名
DLEU1; LEU1; XTP6; Leukemia-associated protein 1; Deleted in lymphocytic leukemia 1; HBV X-transactivated gene 6 protein; HBV XAg-transactivated protein 6
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O43261
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表达区间
1-78aa
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氨基酸序列
MRPCIWIHVHLKPPCRLVELLPFSSALQGLSHLSLGTTLPVILPERNEEQNLQELSHNADKYQMGDCCKEEIDDSIFY
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分子量
34.32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DLEU1, or the Deleted in Lymphocytic Leukemia 1 gene, is a notable long non-coding RNA (lncRNA) located on chromosome 13q14, which has garnered attention due to its potential involvement in various malignancies, particularly in B-cell chronic lymphocytic leukemia (CLL). The gene is known to play a regulatory role in important biological processes, including cell proliferation, survival, and apoptosis, implicating its function in tumorigenesis and cancer progression. Studies have demonstrated that DLEU1 can influence the expression of adjacent protein-coding genes and is often found to be downregulated in cancers, suggesting its role as a tumor suppressor. The exploration of DLEU1 as a recombinant protein provides a unique opportunity to better understand its molecular mechanisms and interactions within cellular pathways. Research involving the recombinant expression of DLEU1 aims to elucidate its functional roles, to investigate its potential as a therapeutic target, and to contribute to the development of novel diagnostic and prognostic tools in cancer management. Further investigations into DLEU1's interactions with other cellular components may reveal insights into its involvement in cancer pathophysiology, paving the way for future studies that could harness its properties for clinical applications, including targeted therapies and personalized medicine strategies in oncological contexts.












