Analytical Data
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Gene name
SPACA1
- Application
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Alternative Names
SACA1_HUMAN; SAMP32; SPACA1; Sperm acrosomal membrane-associated protein 32; Sperm acrosome membrane-associated protein 1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9HBV2
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Expression Region
1-294 aa
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AA Sequence
MSPRGTGCSAGLLMTVGWLLLAGLQSARGTNVTAAVQDAGLAHEGEGEEETENNDSETAENYAPPETEDVSNRNVVKEVEFGMCTVTCGIGVREVILTNGCPGGESKCVVRVEECRGPTDCGWGKPISESLESVRLACIHTSPLNRFKYMWKLLRQDQQSIILVNDSAILEVRKESHPLAFECDTLDNNEIVATIKFTVYTSSELQMRRSSLPATDAALIFVLTIGVIICVFIIFLLIFIIINWAAVKAFWGAKASTPEVQSEQSSVRYKDSTSLDQLPTEMPGEDDALSEWNE
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Molecular Weight
58.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SPACA1 (Sperm Acrosome Associated 1) is a gene that encodes a protein primarily expressed in the male reproductive system, specifically in spermatozoa. The study of SPACA1 has gained significant attention in recent years due to its potential role in sperm-egg interactions and fertilization processes. Researchers have identified SPACA1 as a candidate for understanding male infertility, as its expression is crucial for sperm function, including acrosome reaction and binding to the zona pellucida of oocytes. Advances in reproductive biology and molecular techniques have enabled the examination of SPACA1's structure and function, including its involvement in seminal fluid composition and its interactions with other reproductive proteins. Additionally, the exploration of SPACA1 as a biomarker for male fertility has sparked interest in developing diagnostic tools and therapeutic strategies for managing infertility issues. Given the rising prevalence of infertility, research into SPACA1 provides valuable insights into reproductive health and the underlying mechanisms of fertilization, with the potential for innovative approaches in assisted reproductive technologies. Continued investigation into SPACA1 could lead to breakthroughs in both fundamental reproductive biology and clinical applications, highlighting its importance in the field of reproductive medicine.
