Analytical Data
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Gene name
PRDM7
- Application
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Alternative Names
PRDM7；PFM4；Histone-lysine N-methyltransferase PRDM7
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NQW5
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Expression Region
1-492aa
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AA Sequence
MSPERSQEESPEGDTERTERKPMVKDAFKDISIYFTKEEWAEMGDWEKTRYRNVKMNYNALITVGLRATRPAFMCHRRQAIKLQVDDTEDSDEEWTPRQQVKPPWMAFRGEQSKHQKGMPKASFNNESSLRELSGTPNLLNTSDSEQAQKPVSPPGEASTSGQHSRLKLELRRKETEGKMYSLRERKGHAYKEISEPQDDDYLYCEMCQNFFIDSCAAHGPPTFVKDSAVDKGHPNRSALSLPPGLRIGPSGIPQAGLGVWNEASDLPLGLHFGPYEGRITEDEEAANSGYSWLITKGRNCYEYVDGKDKSSANWMRYVNCARDDEEQNLVAFQYHRQIFYRTCRVIRPGCELLVWSGDEYGQELGIRSSIEPAESLGQAVNCWSGMGMSMARNWASSGAASGRKSSWQGENQSQRSIHVPHAVWPFQVKNFSVNMWNAITPLRTSQDHLQENFSNQRIPAQGIRIRSGNILIHAAVMTKPKVKRSKKGPNS
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Molecular Weight
59.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PRDM7, a member of the PRDM family of proteins, has garnered attention due to its potential roles in various biological processes, including development, differentiation, and gene regulation. Initially identified as a transcription factor, PRDM7 is characterized by its zinc finger motifs, which are crucial for DNA binding and protein interactions. Recent studies indicate that PRDM7 may be involved in the regulation of key signaling pathways, particularly in the context of stem cell biology and cancer. Its ability to modulate gene expression profiles positions PRDM7 as a significant player in maintaining cellular homeostasis and influencing cell fate decisions. Furthermore, investigations into the structure-function relationship of PRDM7 have highlighted its potential as a therapeutic target, as dysregulation of PRDM7 has been implicated in various diseases. Notably, the recombinant expression of PRDM7 facilitates the study of its functional mechanisms, protein interactions, and downstream effects in cellular contexts. As researchers delve deeper into the roles of PRDM7, understanding its biochemical properties and pathways could unveil novel insights into its contributions to development and disease, making it a promising candidate for future therapeutic interventions. Thus, the study of PRDM7 recombinant protein has become a focal point in the quest to elucidate the complex regulatory networks governing cellular biology.
