Analytical Data
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基因名
SOX17
- Application
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别名
FLJ22252; SOX17; SOX17_HUMAN; SRY (sex determining region Y) box 17; SRY box 17 ; SRY related HMG box transcription factor SOX17; Transcription factor SOX-17; Transcription factor SOX17; VUR3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H6I2
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表达区间
1-414 aa
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氨基酸序列
MSSPDAGYAS DDQSQTQSAL PAVMAGLGPC PWAESLSPIG DMKVKGEAPA NSGAPAGAAG RAKGESRIRR PMNAFMVWAK DERKRLAQQN PDLHNAELSK MLGKSWKALT LAEKRPFVEE AERLRVQHMQ DHPNYKYRPR RRKQVKRLKR VEGGFLHGLA EPQAAALGPE GGRVAMDGLG LQFPEQGFPA GPPLLPPHMG GHYRDCQSLG APPLDGYPLP TPDTSPLDGV DPDPAFFAAP MPGDCPAAGT YSYAQVSDYA GPPEPPAGPM HPRLGPEPAG PSIPGLLAPP SALHVYYGAM GSPGAGGGRG FQMQPQHQHQ HQHQHHPPGP GQPSPPPEAL PCRDGTDPSQ PAELLGEVDR TEFEQYLHFV CKPEMGLPYQ GHDSGVNLPD SHGAISSVVS DASSAVYYCN YPDV
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分子量
44.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOX17, a member of the SRY-related HMG-box (SOX) family of transcription factors, plays a crucial role in various biological processes, including embryonic development, cell fate determination, and stem cell maintenance. Its involvement in the regulation of pluripotency and differentiation has garnered significant interest in the fields of developmental biology and regenerative medicine. Mutations or dysregulation of SOX17 have been linked to various diseases, including cancer, highlighting its potential as a therapeutic target. Research on the recombinant SOX17 protein aims to better understand its structural and functional characteristics, as well as its interactions with other cellular proteins. Advances in recombinant DNA technology enable the production of SOX17 in heterologous systems, facilitating the investigation of its role in gene expression and signaling pathways. Additionally, the study of SOX17 may provide insights into its mechanisms of action during lineage specification and its potential applications in stem cell therapy and tissue engineering. Overall, the exploration of recombinant SOX17 protein serves as a promising avenue for unraveling the complexities of developmental processes and developing novel therapeutic strategies.
