Analytical Data
-
Gene name
DUSP26
- Application
-
Alternative Names
DUSP26；DUSP24；LDP4；MKP8；Dual specificity Protein phosphatase 26
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BV47
-
Expression Region
1-211aa
-
AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA
-
Molecular Weight
26 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DUSP26 (Dual Specificity Phosphatase 26) is a member of the dual-specificity phosphatase family, which plays a critical role in regulating various cellular processes by dephosphorylating both tyrosine and serine/threonine residues in target proteins. Due to its involvement in significant signaling pathways, including those modulating proliferation and apoptosis, DUSP26 has garnered attention in cancer research and other disease contexts. Emerging studies indicate that DUSP26 may have distinct functions in different tissues, and its expression levels can be altered in various cancers, suggesting a potential role in tumorigenesis and tumor progression. Understanding the molecular mechanisms and functional implications of DUSP26 is thus crucial for unraveling its contributions to cellular signaling networks. Additionally, as a candidate biomarker or therapeutic target, DUSP26 holds promise in developing new approaches for cancer treatment and prognosis. The focus on recombinant DUSP26 proteins in research aims to elucidate its biochemical properties, determine its specific interactors, and assess its impact on relevant signaling cascades. By generating DUSP26 as a recombinant protein, scientists can conduct in-depth analyses to understand its substrate specificity, regulation, and functional outcomes in vivo and in vitro, paving the way for innovative therapeutic strategies based on targeting DUSP26-driven pathways.
