Analytical Data
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Gene name
FAIM3
- Application
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Alternative Names
FAIM3；FAIM3；TOSO；Immunoglobulin mu Fc receptor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60667
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Expression Region
1-390aa
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AA Sequence
MDFWLWPLYFLPVSGALRILPEVKVEGELGGSVTIKCPLPEMHVRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTLKQYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGKTQKVTLNVHSEYEPSWEEQPMPETPKWFHLPYLFQMPAYASSSKFVTRVTTPAQRGKVPPVHHSSPTTQITHRPRVSRASSVAGDKPRTFLPSTTASKISALEGLLKPQTPSYNHHTRLHRQRALDYGSQSGREGQGFHILIPTILGLFLLALLGLVVKRAVERRKALSRRARRLAVRMRALESSQRPRGSPRPRSQNNIYSACPRRARGADAAGTGEAPVPGPGAPLPPAPLQVSESPWLHAPSLKTSCEYVSLYHQPAAMMEDSDSDDYINVPA
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
FAIM3 (Fas Apoptosis Inhibitory Molecule 3) is a member of the FAIM family, which plays a critical role in regulating apoptosis and immune response. Research has shown that FAIM3 is involved in various cellular processes, including modulation of Fas-mediated apoptosis, control of inflammation, and potential roles in cancer progression. Understanding the function of FAIM3 is crucial, particularly as its dysregulation has been implicated in several diseases, including autoimmune disorders and cancers. The study of FAIM3 as a recombinant protein seeks to elucidate its structure-function relationship, interactions with other signaling molecules, and the molecular mechanisms underlying its anti-apoptotic properties. Through biochemical and biophysical analyses, researchers aim to characterize the recombinant FAIM3 protein, explore its interaction with Fas receptors, and assess its impact on downstream signaling pathways. This research could provide insights into potential therapeutic targets for diseases where FAIM3 is involved, paving the way for novel interventions in pathological conditions driven by apoptosis dysregulation.
