Analytical Data
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Gene name
GATA2
- Application
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Alternative Names
GATA2；Endothelial transcription factor GATA-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P23769
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Expression Region
2-480aa
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AA Sequence
(29 amino acid tag)EVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDV FFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPW LDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGG SGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSS AGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIP TYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVN CGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGT CCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRN RKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFS HSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMGLEESGGGGSPGRRRRRR RRRRR
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Molecular Weight
50 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GATA2 is a zinc-finger transcription factor that plays a critical role in the regulation of various biological processes, including hematopoiesis, lymphocyte development, and angiogenesis. Mutations in the GATA2 gene have been associated with a range of hematological disorders, immune deficiencies, and congenital anomalies. Research into GATA2 recombinant proteins has gained significant attention due to their potential applications in understanding the molecular mechanisms underlying these conditions, as well as in therapeutic strategies. These recombinant proteins enable detailed studies of GATA2's functional domains, protein-protein interactions, and its role in gene regulation. Moreover, by exploring the effects of GATA2 mutations in a controlled environment, researchers aim to elucidate the pathways leading to disease. The generation of GATA2 recombinant proteins also facilitates the development of assays for drug screening and the design of targeted therapies, thereby contributing to advances in personalized medicine for patients suffering from GATA2-related disorders. As a result, the ongoing investigation into GATA2 recombinant proteins stands at the forefront of molecular biology and translational research, with implications for both fundamental understanding and clinical applications.
