Analytical Data
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Gene name
CXorf34
- Application
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Alternative Names
TRMT2B; CXorf34; tRNA; uracil(54)-C(5))-methyltransferase homolog; EC 2.1.1.35; TRM2 homolog
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96GJ1
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Expression Region
1-504aa
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AA Sequence
MAGLKRRVPLHSLRYFISMVGLFSKPGLLPWYARNPPGWSQLFLGTVCKGDFTRVIATKCQKGQKSQKKPSHLGPLDGSWQERLADVVTPLWRLSYEEQLKVKFAAQKKILQRLESYIQMLNGVSVTTAVPKSERLSCLLHPIIPSPVINGYRNKSTFSVNRGPDGNPKTVGFYLGTWRDGNVVCVQSNHLKNIPEKHSQVAQYYEVFLRQSPLEPCLVFHEGGYWRELTVRTNSQGHTMAIITFHPQKLSQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLFGEPYIFEELLSLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQHTSRVLGIELLEQAVEDARWTAAFNGITNSEFHTGQAEKILPGLLKSKEDGQSIVAVVNPARAGLHYKVIQAIRNFRAIHTLVFVSCKLHGESTRNVIELCCPPDPAKKLLGEPFVLQQAVPVDLFPHTPHCELVLLFTR
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Molecular Weight
82.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CXorf34, also known as Chromosome X open reading frame 34, is a protein-coding gene located on the X chromosome, which has garnered attention in recent years due to its potential roles in various biological processes and disease mechanisms. Initially, CXorf34 was identified through genomic studies aiming to uncover novel genes associated with X-linked inheritance patterns. While its precise biological functions remain largely elusive, emerging evidence suggests that CXorf34 may be involved in cellular processes such as cell proliferation and apoptosis, which are critical in health and disease contexts, particularly in cancer research. The expression patterns of CXorf34 have been linked to specific types of tumors, indicating a potential role in tumorigenesis and suggesting that it might serve as a biomarker for certain malignancies. Additionally, its location on the X chromosome raises intriguing questions about its involvement in X-linked disorders and the implications of X chromosome inactivation in females. As researchers continue to explore the functional aspects of CXorf34, recombinant protein studies have become essential for elucidating its interactions, mechanistic pathways, and potential therapeutic applications. The generation and characterization of CXorf34 recombinant proteins could provide insights into its structure-function relationships and facilitate the development of targeted strategies for diseases where CXorf34 expression is altered. Overall, the investigation of CXorf34 and its recombinant form represents a promising avenue for understanding both basic biological processes and the complexities of disease pathology, particularly in neoplastic conditions.
