Analytical Data
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Gene name
COL16
- Application
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Alternative Names
COL16；Zinc finger Protein CONSTANS-LIKE 16
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8RWD0
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Expression Region
1-417aa
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AA Sequence
MMKSLANAVG AKTARACDSC VKRRARWYCA ADDAFLCQSC DSLVHSANPL ARRHERVRLK TASPAVVKHS NHSSASPPHE VATWHHGFTR KARTPRGSGK KNNSSIFHDL VPDISIEDQT DNYELEEQLI CQVPVLDPLV SEQFLNDVVE PKIEFPMIRS GLMIEEEEDN AESCLNGFFP TDMELEEFAA DVETLLGRGL DTESYAMEEL GLSNSEMFKI EKDEIEEEVE EIKAMSMDIF DDDRKDVDGT VPFELSFDYE SSHKTSEEEV MKNVESSGEC VVKVKEEEHK NVLMLRLNYD SVISTWGGQG PPWSSGEPPE RDMDISGWPA FSMVENGGES THQKQYVGGC LPSSGFGDGG REARVSRYRE KRRTRLFSKK IRYEVRKLNA EKRPRMKGRF VKRASLAAAA SPLGVNY
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
COL16, or collagen type XVI, is an essential component of the extracellular matrix and plays a crucial role in tissue structure and stability. Its unique properties have drawn significant research interest, particularly concerning its involvement in various physiological and pathological processes. Studies suggest that COL16 is implicated in cellular adhesion, migration, and proliferation, which are vital for tissue development and repair. Additionally, it has been linked to several diseases, including fibrosis and certain types of cancer, where altered COL16 expression can influence tumor progression and metastasis. Researchers have been focusing on the recombinant production of COL16 to better understand its functions and mechanisms. By using recombinant technology, scientists can produce COL16 in a controlled manner, facilitating investigations into its biological roles and potential therapeutic applications. Understanding COL16's structure-function relationships may also pave the way for developing novel strategies to target diseases associated with collagen dysregulation, thereby enhancing tissue engineering and regenerative medicine approaches. Overall, COL16 represents a promising focal point in the exploration of extracellular matrix components and their implications in health and disease.
