Analytical Data
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Gene name
ART1
- Application
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Alternative Names
ART1；APPILS；ARTS1；KIAA0525；Endoplasmic reticulum aminopeptidase 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P52961
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Expression Region
23-295aa
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AA Sequence
QSHPITRRDLFSQEIQLDMALASFDDQYAGCAAAMTAALPDLNHTEFQANQVYADSWTLASSQWQERQARWPEWSLSPTRPSPPPLGFRDEHGVALLAYTANSPLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLGSGQRPPRCHQVFRGVHGLRFRPAGPRATVRLGGFASASLKHVAAQQFGEDTFFGIWTCLGAPIKGYSFFPGEEEVLIPPFETFQVINASRLAQGPARIYLRALGKHSTYNCEYIKDKKCKSGPCHLDNS
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Molecular Weight
32.5kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ART1 (ADP-ribosyltransferase 1) is an important enzyme involved in the post-translational modification of proteins through ADP-ribosylation, a process that plays a pivotal role in various cellular functions such as signal transduction, DNA repair, and modulation of protein interactions. The significance of ART1 has been highlighted in recent studies that link its activity to several pathological conditions, including cancer and autoimmune diseases. This has spurred extensive research into the molecular mechanisms underlying ART1's function, its substrate specificity, and the potential implications of its dysregulation in disease progression. Recombinant ART1 proteins have emerged as valuable tools for investigating its biological roles, allowing for the precise examination of its enzymatic activity and interaction with cellular targets. Additionally, insights gained from the study of ART1's structure and function may pave the way for the development of novel therapeutic strategies aimed at modulating its activity to restore normal cellular processes. The exploration of ART1's potential as a biomarker for disease diagnosis and prognosis further underscores its relevance in the field of molecular medicine. Ultimately, this research not only enhances our understanding of ART1's fundamental biological roles but also opens up new avenues for targeted interventions in diseases associated with its aberrant regulation.
