Analytical Data
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Gene name
SLC35D3
- Application
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Alternative Names
bA55K22.3; Frc fringe like 1; FRCL1; Fringe connection like protein 1; Fringe connection-like protein 1; MGC102873; S35D3_HUMAN; SLC35D3; Solute carrier family 35 member D3
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5M8T2
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Expression Region
1-416 aa
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AA Sequence
MRQLCRGRVLGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIAVPPFGLSLARSFAGVAVLSTLQSSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTCGAALAGAGDLTGDPIGYVTGVLAVLVHAAYLVLIQKASADTEHGPLTAQYVIAVSATPLLVICSFASTDSIHAWTFPGWKDPAMVCIFVACILIGCAMNFTTLHCTYINSAVTTSFVGVVKSIATITVGMVAFSDVEPTSLFIAGVVVNTLGSIIYCVAKFMETRKQSNYEDLEAQPRGEEAQLSGDQLPFVMEELPGEGGNGRSEGGEAAGGPAQESRQEVRGSPRGVPLVAGSSEEGSRRSLKDAYLEVWRLVRGTRYMKKDYLIENEELPSP
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Molecular Weight
70.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC35D3 is a member of the SLC35 family of solute carriers, which are integral membrane proteins involved in the transport of a variety of solutes, including nucleotide sugars and other metabolites. The study of SLC35D3 is crucial as it plays a significant role in cellular processes such as glycosylation, a post-translational modification essential for protein maturation and functionality. Dysregulation of SLC35D3 has been implicated in various diseases, including metabolic disorders and certain cancers, making it an important target for therapeutic research. Recent advances in molecular biology techniques, including recombinant protein expression, have facilitated the generation and study of SLC35D3 to better understand its structure-function relationships, transport mechanisms, and interactions with other cellular components. Investigating SLC35D3 at the molecular level may provide insights into its physiological roles and potential as a biomarker or therapeutic target. Overall, the research surrounding SLC35D3 is vital for elucidating its contributions to health and disease, paving the way for innovative treatment strategies that leverage its biological functions.
