Analytical Data
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基因名
SLC26A1
- Application
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别名
EDM4; S26A1_HUMAN; SAT 1; SAT-1; SAT1; Slc26a1; solute carrier family 26 (anion exchanger); member 1; solute carrier family 26 (sulfate transporter); member 1; Solute carrier family 26 member 1; sulfate anion tranporter AT1; Sulfate anion transporter 1; sulfate transporter; sulfate/anion transporter SAT 1 protein; sulfate/anion transporter SAT1 protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H2B4
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氨基酸序列
MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL
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分子量
77.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC26A1, a member of the SLC26 family of anion transporters, plays a crucial role in ion transport and homeostasis, particularly in the transport of sulfate and bicarbonate ions. Its importance is underscored by its involvement in various physiological processes, including the regulation of pH and the maintenance of electrolyte balance. Mutations in the SLC26A1 gene have been linked to various disorders, such as congenital chloride diarrhea, highlighting its significance in human health. The investigation of SLC26A1 recombinant protein is critical for understanding its functional mechanisms, structure-function relationships, and interactions with other cellular components. By producing and purifying recombinant SLC26A1, researchers can analyze its transport properties, substrate specificity, and regulatory mechanisms, providing insights into how alterations in its function may lead to disease. Furthermore, studying this protein in a controlled experimental setting allows for the development of targeted therapeutic strategies aimed at correcting SLC26A1-related dysfunctions. Overall, the research on SLC26A1 recombinant protein is pivotal for advancing our understanding of ion transport processes and their implications in biotechnology and medicine.
