Analytical Data
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Gene name
SLC26A1
- Application
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Alternative Names
EDM4; S26A1_HUMAN; SAT 1; SAT-1; SAT1; Slc26a1; solute carrier family 26 (anion exchanger); member 1; solute carrier family 26 (sulfate transporter); member 1; Solute carrier family 26 member 1; sulfate anion tranporter AT1; Sulfate anion transporter 1; sulfate transporter; sulfate/anion transporter SAT 1 protein; sulfate/anion transporter SAT1 protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H2B4
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AA Sequence
MDESPEPLQQGRGPVPVRRQRPAPRGLREMLKARLWCSCSCSVLCVRALVQDLLPATRWLRQYRPREYLAGDVMSGLVIGIILVPQAIAYSLLAGLQPIYSLYTSFFANLIYFLMGTSRHVSVGIFSLLCLMVGQVVDRELQLAGFDPSQDGLQPGANSSTLNGSAAMLDCGRDCYAIRVATALTLMTGLYQVLMGVLRLGFVSAYLSQPLLDGFAMGASVTILTSQLKHLLGVRIPRHQGPGMVVLTWLSLLRGAGQANVCDVVTSTVCLAVLLAAKELSDRYRHRLRVPLPTELLVIVVATLVSHFGQLHKRFGSSVAGDIPTGFMPPQVPEPRLMQRVALDAVALALVAAAFSISLAEMFARSHGYSVRANQELLAVGCCNVLPAFLHCFATSAALAKSLVKTATGCRTQLSSVVSATVVLLVLLALAPLFHDLQRSVLACVIVVSLRGALRKVWDLPRLWRMSPADALVWAGTAATCMLVSTEAGLLAGVILSLLSLAGRTQRPRTALLARIGDTAFYEDATEFEGLVPEPGVRVFRFGGPLYYANKDFFLQSLYSLTGLDAGCMAARRKEGGSETGVGEGGPAQGEDLGPVSTRAALVPAAAGFHTVVIDCAPLLFLDAAGVSTLQDLRRDYGALGISLLLACCSPPVRDILSRGGFLGEGPGDTAEEEQLFLSVHDAVQTARARHRELEATDAHL
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Molecular Weight
77.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC26A1, a member of the SLC26 family of anion transporters, plays a crucial role in ion transport and homeostasis, particularly in the transport of sulfate and bicarbonate ions. Its importance is underscored by its involvement in various physiological processes, including the regulation of pH and the maintenance of electrolyte balance. Mutations in the SLC26A1 gene have been linked to various disorders, such as congenital chloride diarrhea, highlighting its significance in human health. The investigation of SLC26A1 recombinant protein is critical for understanding its functional mechanisms, structure-function relationships, and interactions with other cellular components. By producing and purifying recombinant SLC26A1, researchers can analyze its transport properties, substrate specificity, and regulatory mechanisms, providing insights into how alterations in its function may lead to disease. Furthermore, studying this protein in a controlled experimental setting allows for the development of targeted therapeutic strategies aimed at correcting SLC26A1-related dysfunctions. Overall, the research on SLC26A1 recombinant protein is pivotal for advancing our understanding of ion transport processes and their implications in biotechnology and medicine.
