Analytical Data
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基因名
CREBL1
- Application
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别名
ATF6B; CREBL1; G13Cyclic AMP-dependent transcription factor ATF-6 beta; cAMP-dependent transcription factor ATF-6 beta; Activating transcription factor 6 beta; ATF6-beta; Protein G13
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99941
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表达区间
1-318aa
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氨基酸序列
MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDGSSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGEVLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASLLSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTRKPPLQPKPVVLTTVPMPSRAVSPSTTVLLQSLVQPPPGTEEGEKGRAWWLTPVIPALWEAEAGESPEVRSLRPAWPTW
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分子量
60.61 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CREBL1, or CREB-like protein 1, is a member of the CREB (cAMP response element-binding protein) family of transcription factors, which play crucial roles in regulating gene expression in response to various cellular signals. The research interest in CREBL1 has expanded due to its potential implications in diverse biological processes, including cell proliferation, differentiation, and apoptosis. Recent studies suggest that CREBL1 may be involved in the regulation of several signaling pathways, especially those related to stress responses and metabolic processes. Its expression has been linked to various diseases, including cancer and neurological disorders, making it a target for therapeutic interventions. The recombinant expression of CREBL1 offers opportunities to explore its functional mechanisms and interactions at a molecular level, facilitating the understanding of its role in health and disease. Protein-based studies, including structural analysis and biochemical assays, can provide insights into how CREBL1 modulates gene expression and cellular responses, further elucidating its potential as a biomarker or therapeutic target. As such, the generation and characterization of CREBL1 recombinant protein are critical for advancing research in cellular signaling and disease pathology, paving the way for novel treatments and interventions.












