Analytical Data
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基因名
MON1A
- Application
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别名
MON1A;SAND1;Vacuolar fusion Protein MON1 homolog A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86VX9
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表达区间
205-555aa
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氨基酸序列
DGYKVVFVRRSPLVLVAVARTRQSAQELAQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPSFLMGAARCLPLAAAVRDTVSASLQQARARSLVFSILLARNQLVALVRRKDQFLHPIDLHLLFNLISSSSSFREGEAWTPVCLPKFNAAGFFHAHISYLEPDTDLCLLLVSTDREDFFAVSDCRRRFQERLRKRGAHLALREALRTPYYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYTSEEEQERLLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWIRKEEDRLFILTPLTY
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分子量
56.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MON1A is a crucial protein involved in intracellular transport and membrane trafficking, playing a significant role in the regulation of vesicle dynamics and endosomal function. It is part of the conserved MON1/CzcE protein family, which has garnered attention due to its implications in various cellular processes, including autophagy and lysosomal function. Research into MON1A has expanded significantly in recent years, particularly in the context of its potential links to neurodegenerative diseases and cancer. Studies have indicated that MON1A is essential for the maturation of endosomes and the recycling of receptors, making it a key player in maintaining cellular homeostasis. Its dysfunction can lead to impaired cell signaling and contribute to disease progression. Given its importance, scientists are keenly investigating the biochemical pathways involving MON1A, the protein's interactions with other cellular components, and its potential as a therapeutic target. Furthermore, advances in recombinant protein technology have enabled researchers to produce MON1A in vitro, allowing for detailed structural and functional analyses. This research holds promise for elucidating the molecular mechanisms governing cellular transport processes and could lead to novel strategies for therapeutic intervention in diseases associated with MON1A dysfunction. Understanding the precise role of MON1A in cellular dynamics may ultimately pave the way for the development of targeted therapies that can enhance cell function and combat disease effectively.












