Analytical Data
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Gene name
CPXCR1
- Application
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Alternative Names
CPXCR1CPX chromosomal region candidate gene 1 protein; Cancer/testis antigen 77; CT77
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N123
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Expression Region
1-301aa
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AA Sequence
MSSPTKEGSDTAGNAHKNSENEPPNDCSTDIESPSADPNMIYQVETNPINREPGTATSQEDVVPQAAENSELETEIQKDQREEDLKEELLLLQTPIPRKLVSHKPLNDRSRSHSGKVEMKANNFPINHKTRFRLSTSWRVPFINSHEIRSMILHLLCDRYFSQAAGCQNTMWVKRKYIACLYHPNSFTHHERAITFRRPSRVHYYRPLTERMTSGKFCKSTDTKGKCRFRAIVRSVLFVSQIQIESIFNIKGFVDILTYIHTMNVMITNTNNGWKYFCPICGRLFNTYSELRQHSCSSSGN
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Molecular Weight
61.1 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPXCR1, a receptor belonging to the chemokine receptor family, has garnered significant attention in recent years due to its potential roles in immune responses and various pathological conditions. Research on CPXCR1 has particularly intensified in the context of its involvement in hematopoietic processes and its implication in inflammation and autoimmune diseases. The receptor is believed to play a crucial role in regulating leukocyte trafficking, influencing how immune cells migrate to sites of inflammation or injury. Furthermore, studies have suggested that CPXCR1 may also have a role in cancer progression by modulating the tumor microenvironment and facilitating metastasis. As a result, the recombinant production of CPXCR1 has become a pivotal focus for researchers aiming to better understand its structure-function relationships and interactions with ligands. The ability to generate CPXCR1 as a recombinant protein allows for detailed biochemical studies, paving the way for the development of potential therapeutic strategies targeting this receptor. By employing techniques such as site-directed mutagenesis and advanced structural analysis, scientists hope to elucidate the molecular mechanisms underlying CPXCR1 signaling pathways. This research not only aims to unravel the complexities of immune regulation but also aspires to contribute to the design of novel treatments for conditions associated with dysregulated CPXCR1 activity, making it a crucial area of investigation in the field of immunology and translational medicine.
