Analytical Data
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Gene name
CPXM1
- Application
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Alternative Names
CPXM1; CPX1; CPXM; UNQ3015/PRO9782Probable carboxypeptidase X1; EC 3.4.17.-; Metallocarboxypeptidase CPX-1
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96SM3
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Expression Region
1-734aa
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AA Sequence
MWGLLLALAAFAPAVGPALGAPRNSVLGLAQPGTTKVPGLTPALHSSPAQPPAETANGTSEQHVRIRVIKKKKVIMKKRKKLTLTRPTPLVTAGPLVTPTPAGTLDPAEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAEEQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMDAVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEAPASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTKTPKQRLRELLAAGAKVPPDLRRRLERLRGQKD
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Molecular Weight
108.1 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CPXM1, or Carboxypeptidase X (M14 Family), is a novel protein that has garnered significant interest in recent years due to its potential roles in various biological processes and diseases. It is part of the M14 family of metallo-carboxypeptidases, known for their ability to cleave C-terminal residues from target proteins, thus participating in protein maturation, processing, and signaling pathways. Recent studies have highlighted the involvement of CPXM1 in cellular functions such as cell adhesion, migration, and immune responses, which suggests a possible link to cancer metastasis and other pathological conditions. The expression of CPXM1 has been correlated with various tumors, including breast cancer and colorectal cancer, raising intriguing questions about its potential as a biomarker for diagnosis or prognosis. Moreover, understanding the enzymatic activity and substrate specificity of CPXM1 could provide insights into how it influences tumorigenesis and immune evasion. Consequently, researchers are focused on characterizing recombinant CPXM1 to elucidate its structure-function relationships, enzymatic mechanisms, and interaction with cellular partners. These investigations could pave the way for new therapeutic strategies targeting CPXM1, ultimately enhancing cancer treatment and improving patient outcomes.
