Cat: PA1000-7230

Recombinant Human NRXN3 Protein,His

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Analytical Data

  • 基因名

    NRXN3

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    NRXN3;KIAA0743;Neurexin-3-beta

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9HDB5-2

  • 表达区间

    1-357aa

  • 氨基酸序列

    MHLRIHARRS PPRRPAWTLG IWFLFWGCIV SSVWSSSNVA SSSSTSSSPG SHSQHEHHFH GSKHHSVPIS IYRSPVSLRG GHAGATYIFG KSGGLILYTW PANDRPSTRS DRLAVGFSTT VKDGILVRID SAPGLGDFLQ LHIEQGKIGV VFNIGTVDIS IKEERTPVND GKYHVVRFTR NGGNATLQVD NWPVNEHYPT GRQLTIFNTQ AQIAIGGKDK GRLFQGQLSG LYYDGLKVLN MAAENNPNIK INGSVRLVGE VPSILGTTQT TSMPPEMSTT VMETTTTMAT TTTRKNRSTA SIQPTSDDLV SSAECSSDDE DFVECEPSTG RSANPTEPGI RRVPGASEVI RESSSTT

  • 分子量

    36 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

NRXN3, or Neurexin 3, is a member of the neurexin family, which plays a crucial role in synapse formation and function in the nervous system. This protein is implicated in various neurodevelopmental disorders, including autism spectrum disorders (ASD) and schizophrenia, making it a significant target for biomedical research. The gene encoding NRXN3 has been linked to genetic variations that contribute to these conditions, highlighting its potential role in the pathophysiology of neuropsychiatric disorders. Researchers are particularly interested in the structure and function of NRXN3, as understanding its molecular interactions could provide insights into synaptic dysfunction found in these diseases. Recombinant NRXN3 proteins are essential for studying these interactions and exploring their effects in model systems. By producing and characterizing NRXN3 as a recombinant protein, scientists can investigate its binding affinity with other synaptic proteins, elucidate its role in synaptic signaling, and evaluate how mutations or variations in this protein affect neural function. This research not only enhances our foundational knowledge of synaptic biology but also paves the way for potential therapeutic strategies aimed at targeting NRXN3-related pathways in autism and other neurodevelopmental disorders. Thus, the study of NRXN3 recombinant proteins represents a vital intersection of molecular neuroscience and clinical research, with the potential to advance our understanding of complex neurodevelopmental conditions.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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