Analytical Data
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基因名
CLDN20
- Application
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别名
CLDN20; Claudin-20
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P56880
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表达区间
1-219aa
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氨基酸序列
MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNIITAIVQLHGLWMDCTWYSTGMFSCALKHSILSLPIHVQAARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHASFAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNKHEPGGAIYIGFISAMLLFISGMIFCTSCIKRNPEARLDPPTQQPISNTQLENNSTHNLKDYV
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分子量
49.83 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CLDN20, or Claudin 20, is a member of the claudin family of proteins that play a crucial role in the formation and maintenance of tight junctions between epithelial cells. These junctions are essential for creating selective barriers that regulate the passage of ions, solutes, and water between tissues. While most claudins have been well-studied, the specific functions and mechanisms of CLDN20 remain less understood. Research has indicated that CLDN20 may be involved in various physiological processes, including renal function and the integrity of the blood-brain barrier, suggesting its potential relevance in both health and disease. Dysregulation of claudin expression has been linked to several pathological conditions, including cancer and kidney diseases, highlighting the importance of elucidating its role at the molecular level. The study of CLDN20 recombinant proteins aims to investigate its structural properties, binding interactions, and functional capabilities within cell models. Understanding the role of CLDN20 could provide insights into its involvement in tight junction dynamics and its potential as a therapeutic target or biomarker for relevant diseases. As research continues, the development of CLDN20 recombinant proteins offers a promising approach to advance our knowledge of this protein’s biological significance and its implications in various cellular processes.












