Recombinant Human CLDN17 Protein，GST

CLDN17, or Claudin-17, is a member of the claudin family of proteins, which are integral components of tight junctions in epithelial tissues. These proteins play a crucial role in maintaining the integrity of cellular barriers and regulating paracellular permeability. Recent studies have identified CLDN17 as a key player in various physiological and pathological processes, particularly in the context of kidney function and gastrointestinal health. Notably, CLDN17 is prominently expressed in the renal proximal tubules and has been implicated in processes such as ion transport, water reabsorption, and the maintenance of homeostasis. Dysregulation of CLDN17 expression has been associated with several conditions, including renal diseases and cancers, where it may contribute to altered cell proliferation and invasion. Given its significant biological roles, research into the recombinant production of CLDN17 protein has gained attention. The ability to produce this protein in a recombinant form can facilitate detailed studies of its structural properties, interactions with other cellular components, and functional assays to elucidate its role in tight junction dynamics. Furthermore, understanding CLDN17's mechanisms of action may provide insights for potential therapeutic targets in diseases where tight junction integrity is compromised. Thus, the study of recombinant CLDN17 not only enhances our comprehension of epithelial physiology but also opens avenues for innovative therapeutic strategies targeting claudin-related pathologies.