Analytical Data
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Gene name
TAF11
- Application
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Alternative Names
TAF11；TAF2I；Transcription initiation factor TFIID subunit 11
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q15544
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Expression Region
1-211aa
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AA Sequence
MDDAHESPSDKGGETGESDETAAVPGDPGATDTDGIPEETDGDADVDLKEAAAEEGELESQDVSDLTTVEREDSSLLNPAAKKLKIDTKEKKEKKQKVDEDEIQKMQILVSSFSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFVGEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIPNSKHKKIIFF
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Molecular Weight
50.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TAF11 is a key component of the TFIID complex, which is essential for the initiation of transcription by RNA polymerase II. This protein plays a critical role in the regulation of gene expression, influencing various cellular processes, including cell differentiation, proliferation, and response to environmental signals. As part of the TFIID complex, TAF11 interacts with other TAFs and transcription factors, facilitating the binding of RNA polymerase II to core promoter elements. Research into TAF11 recombinant proteins has gained momentum due to their potential applications in understanding transcriptional regulation and their implications in various diseases, including cancer. By producing recombinant TAF11, scientists aim to elucidate its structural and functional characteristics, as well as its interactions with other transcriptional components. This knowledge could provide insights into its role in transcriptional control and its potential as a therapeutic target. Additionally, the study of TAF11 may contribute to the broader understanding of the molecular mechanisms underlying transcriptional dysregulation in various pathological conditions. Advances in recombinant protein techniques and biochemical assays are crucial for characterizing TAF11's functionality and for exploring its impact on gene expression networks. Overall, the exploration of TAF11 as a recombinant protein is an important step towards unraveling the complexities of gene regulation and identifying novel strategies for disease intervention.
